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Published: 2021-12-09
Abstract Views: 243
DOI: https://doi.org/10.52163/yhc.v62i7%20(2021).240
Issue
Vol. 62 No. 7 (2021)
Section
Articles
How to Cite
Hải, T. X. ., & Trâm, Q. A. . (2021). CHARACTERISTICS AND THE EFFECTIVENESS OF ANTENATAL SCREENING FOR CHRONMOSOMAL ABNORMALITIES IN HIGH-RICK PREGNANT WOMAN IN NGHE AN (2020 – 2021). Vietnam Journal of Community Medicine, 62(7 (2021). https://doi.org/10.52163/yhc.v62i7 (2021).240

CHARACTERISTICS AND THE EFFECTIVENESS OF ANTENATAL SCREENING FOR CHRONMOSOMAL ABNORMALITIES IN HIGH-RICK PREGNANT WOMAN IN NGHE AN (2020 – 2021)

Tang Xuan Hai1, Que Anh Tram2
1 Nghe An Obstetric and Pediatrics Hospital
2 Nghe An Priendship General Hospital

Main Article Content

Abstract

Characteristics and the effectiveness of antenatal screening for chromosomal abnormalities in high-risk pregnant women in Nghe An (2020 – 2021), Screening for fetal chromosomal abnormalities is of great significance in limiting birth defects.


Objective and method: To figure out chromosomal abnormalities and the value of some prenatal screening tests at Nghe An Obstetrics and Gynecology Hospital (2020-2021). Methods: 121 pregnant women who had an indication for amniocentesis were undergone ultrasound, Double test, Triple test and amniocentesis for a karyotype analysis.


Results: The mean age of the participants was 32 ± 6.69 years. 62.8% of fetuses had abnormalities on ultrasound, among them the most common ones were nuchal translucency thickness (12.6%) and aplasia of the nasal bone (5.5%). The rate of chromosomal abnormality was 15.7%, of which the most common was Edwards syndrome (36.8%) followed by Down syndrome (31.6%).There was no association between fetal chromosomal abnormalities and maternal age of the pregnancy, history of pregnancy with malformations, miscarriage or family history of genetic disease.


Conclusion: Ultrasound and blood screening tests have high sensitivity, high negative predictive value but low sensitivity and low positive predictive value in predicting abnormalities of fetal chromosomes.

Article Details

Keywords

Chromosomal abnormalities, amniocentesis, pregnancy.

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