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Published: 2022-11-18
Abstract Views: 113
DOI: https://doi.org/10.52163/yhc.v63i7.484
Issue
Vol. 63 No. chuyên đề 2-HN Y học Giới tính (2022)
Section
Articles
How to Cite
Yến, Q. T. ., Lâm, Q. H. ., Thụy, Đoàn M. ., Hảo, V. T. ., Trang, N. H. ., Nam, N. T. ., & Đức, C. V. . (2022). VAS DEFERENS CHARACTERISTIC AND RELATED FACTORS TO SPERM COLLECTING BY MICROTESE IN PATIENTS WITH NON OBSTRUCTIVE AZOOSPERMIA. Vietnam Journal of Community Medicine, 63(chuyên đề 2-HN Y học Giới tính). https://doi.org/10.52163/yhc.v63i7.484

VAS DEFERENS CHARACTERISTIC AND RELATED FACTORS TO SPERM COLLECTING BY MICROTESE IN PATIENTS WITH NON OBSTRUCTIVE AZOOSPERMIA

Quach Thi Yen1, Quan Hoang Lam2, Doan Minh Thuy1, Vu Thi Hao3, Nguyen Huyen Trang1, Nguyen Truong Nam1, Chu Van Duc1
1 Vietnam University of Traditional Medicine
2 Vietnam Military Medical University
3 Thai Nguyen University of Medicine and Pharmacy

Main Article Content

Abstract

Objectives: To describe the characteristics of the seminiferous tubules and the relationship to
sperm collection by micro-TESE (Microdissection testicular sperm extraction - micro TESE)
in patients with nonobstructive azoospermia (NOA). Subjects and research methods: 132
NOA patients were performed micro TESE at the Military Clinical Embryo Institute - Vietnam
Military Medical University from 5/2017 to 12/2019. Results: Histopathology of 132 NOA
patients showed that the rate of hypospermatogenesis (HP), maturation arrest (MA), Sertoli
cell only syndrome (SCOS) and hyalinization was 8.33%, 20.45%, 59.85%, and 11.36%,
respectively. The diameter of the seminiferous tubules in patients with NOA was smaller
than the normal value, in which the fibrous sheath thickness was thicker. The epithelial
cells reduced severely. The percentage of patients with sperm collection was 40.15%. The
probability of finding spermatozoa in patients with normal seminiferous tubule diameter and
fibrous sheath thickness was 5.58 times and 6.20 times compared with patients out of the
normal values. The probability of finding spermatozoa in patients with Johnsen score ≥ 8
was 6.66 times higher than that in patients with Johnsen score < 8. Conclusion: There was a
difference in characteristics of the seminiferous tubules in NOA patients compared with the
normal value. Histopathology is one of the factors predicting the success of the micro TESE
method. There was a relationship between seminiferous tubule diameter, fibrous sheath
thickness and Johnsen score to sperm collection rate in NOA patients.

Article Details

Keywords

Microsurgical method to collect sperm from testicles; Non-obstruction azoospermia; Sperm collection; testicular histology.

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