42. THE STUDY OF ENDOBRONCHIAL ULTRASOUND IN DIAGNOSING MEDIASTINAL LESIONS IN NATIONAL LUNG HOSPITAL, 2021
Main Article Content
Abstract
Objective: Endobronchial ultrasound – guided tranbronchial neede aspiration (EBUS-TBNA) is a new method for the diagnosis of mediastinal lesions located adjacent to the central airway. The purpose of this study was to evaluate the result of EBUS-TBNA for the diagnosis of mediastinal lesions.
Methods: We descriptively studied the results of patients who underwent EBUS-TBNA between 6/2021 to 6/2022. Final diagnosis were determined by EBUS-TBNA, surgery and (or) clinical follow-up.
Results: A total of 81 patients, of whom 52 (64,2%) were male and 29 (35,8%) were female. The mean age was 55,20±14,47 years. The final diagnoses were 35 malignant mediastinal and 46 benign mediastinal. The EBUS-TBNA was diagnostic in 70 of 81 patients: Malignant 31, tuberculosis 25, nonspecific inflammatory 10, mediastinal goiter 1, sarcoidosis 2, normal 1. The diagnostic accuracy of EBUS-TBNA was 86,4%, 84,8% for benign lesions and 88,6% for malignant lesions. The sensitivity, specificity, positive predictive value, negative predictive value was 85,7%, 100%, 100% and 91,5% respectively. There were no complications.
Conclusions: The diagnostic value of EBUS-TBNA is high for mediastinal lesions located adjacent to the central airway.
Article Details
Keywords
Endobronchial ultrasound, transbronchial needle aspiration, mediastinal tumor.
References
application of endobronchial ultrasound-guided
transbronchial needle aspiration: A single institution
experience. BMC Pulm Med. 2019;19(1):155.
[2] Agarwal R, Srinivasan A, Aggarwal AN et al.,
Effiacy and safety of convex probe EBUS-TBNA in
sarcoidosis: A systematic review and meta-analysis.
Respir Med.2012;106 (6):883-92.
[3] Sun J, Teng J, Yang H et al., Endobronchial ultrasound-
guided transbronchial needle aspiration in
diagnosing intrathoracic tuberculosis. Ann Thorac
Surg. 2013; 96 (6):2021-7.
[4] Yasufuku K, Nakajima T, Fujiwara T et al., Utility of
endobronchial ultrasound-guided transbronchial needle
aspiration in the diagnosis of mediastinal masses of
unknown etiology. Ann Thorac Surg. 2011;91 (3):831-836.
[5] Evison M, Crosbie PA, Morris J et al., A study
of patients with isolated mediastinal and hilar
lymphadenopathy undergoing EBUS-TBNA.
BMJ Open Respir Res, 1 (1), e000040, 2014.
[6] Korkmaz C, Demirbas S, Vatansev H, The value
of endobronchial ultrasound-guided transbronchial
needle aspiration, 18-fluorodeoxyglucose
positron emission tomography/computed tomography,
and ultrasonography imaging techniques in the
diagnosis of mediastinal and/or hilar malignant, anthracotic,
and other benign lymph nodes. Medicine (Baltimore),
100 (7),e24728, 2021.
[7] Ortakoylu MG, Iliaz S, Bahadir A et al., Diagnostic
value of endobronchial ultrasound-guided
transbronchial needle aspiration in various lung
diseases. J Bras Pneumol, 41 (5), 2015, 410-414.
[8] Murthi M, Donna E, Arias S et al., Diagnostic
Accuracy of Endobronchial Ultrasound-Guided
Transbronchial Needle Aspiration (EBUS-TBNA) in
Real Life. Frontiers in medicine, 7, 118,2020.
[9] Isobel Dugdale, See Ling Tan, Muhammad Niazi
et al., Diagnostic yield and safety of EBUS-TBNA: single
centre experience over 10 years. European Respiratory
Journal, 62 (suppl 67),PA1793, 2023.