29. CASE REPORT: RELAPSING POLYCHONDRITIS CAUSING AIRWAY STENOSIS AT NATIONAL LUNG HOSPITAL IN 2023

Duong Huu Hieu1, Cung Van Tan1, Nguyen Kim Cuong1, Hoang Huong Giang1
1 National Lung Hospital

Main Article Content

Abstract

Introduction: Relapsing polychondritis is a rare disease, difficult to diagnose, and easily confused due to atypical symptoms. Airway involvement in relapsing polychondritis is a poor prognostic sign that can be life-threatening.


Objective: Describing a case of relapsing polychondritis causing airway stenosis, providing clinical characteristics and laboratory data, contributing to scientific data, helping towards early diagnosis of the disease, and presenting some treatment methods.


Case report: A 55-year-old male patient was hospitalized with severe respiratory failure. Laryngotracheal, auricular, and nasal chondritis help diagnose the disease. The patient was treated with corticosteroids and a tracheostomy.


Discussion: Discussing diagnostic criteria, diagnostic difficulties, and treatment methods, emphasizing the severity of airway involvement in relapsing polychondritis.


Conclusion: Information from the case report and discussion shows the importance of early and precise diagnosis in the treatment and prevention of irreversible complications in patients with relapsing polychondritis causing airway stenosis.

Article Details

References

[1] Arnaud L, Costedoat-Chalumeau N, Mathian A
et al., French practical guidelines for the diagnosis
and management of relapsing polychondritis.
Rev Med Interne, 44(6), 2023, pp. 282-294.
[2] Mathian A, Miyara M, Cohen-Aubart F et al.,
Relapsing polychondritis: A 2016 update on
clinical features, diagnostic tools, treatment and
biological drug use. Best Practice & Research
Clinical Rheumatology, 30(2), 2016, pp. 316-
333.
[3] Winter G, Löffelmann T, Chaya S et al., Relapsing
Polychondritis with Tracheobronchial
Involvement: A Detailed Description of Two Pediatric
Cases and Review of the Literature. Klin
Padiatr, 236(2), 2024, pp. 97-105.
[4] Ernst A, Rafeq S, Boiselle P et al., Relapsing
polychondritis and airway involvement. Chest,
135(4), 2009, pp. 1024-1030.
[5] de Montmollin N, Dusser D, Lorut C et al., Tracheo-
bronchial involvement of relapsing polychondritis.
Autoimmunity Reviews, 18(9), 2019,p. 102353.
[6] Dubey S, Gelder C, Pink G et al., Respiratory
subtype of relapsing polychondritis frequently
presents as difficult asthma: A descriptive study
of respiratory involvement in relapsing polychon-
dritis with 13 patients from a single UK
centre. ERJ Open Res, 7(1), 2021.
[7] Borgia F, Giuffrida R, Guarneri F et al., Relapsing
Polychondritis: An Updated Review. Biomedicines,
6(3), 2018.
[8] McAdam L P, O'Hanlan M A, Bluestone R et al.,
Relapsing polychondritis: Prospective study of
23 patients and a review of the literature. Medicine
(Baltimore), 55(3), 1976, pp. 193-215.
[9] Damiani JM, Levine HL, Relapsing polychondritis--
report of ten cases. Laryngoscope, 89(6 Pt
1), 1979, pp. 929-46.
[10] Michet CJ Jr., McKenna CH, Luthra HS et al.,
Relapsing polychondritis. Survival and predictive role
of early disease manifestations. Ann Intern Med,
104(1), 1986, pp. 74-8.