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Published: 2026-08-25
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Vol. 67 No. CĐ12- Bệnh viện Ung bướu Nghệ An
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Articles
How to Cite
Tuấn, L. V., Dương, T. B., Hưng, T. N. K., & Tú, Đào T. (2026). APPLICATION OF INTRAOPERATIVE FROZEN SECTION IN SECOND-STAGE REIMPLANTATION FOR CHRONIC PERIPROSTHETIC HIP JOINT INFECTION. Vietnam Journal of Community Medicine, 67(CĐ12- Bệnh viện Ung bướu Nghệ An). Retrieved from https://tapchiyhcd.vn/index.php/yhcd/article/view/6275

APPLICATION OF INTRAOPERATIVE FROZEN SECTION IN SECOND-STAGE REIMPLANTATION FOR CHRONIC PERIPROSTHETIC HIP JOINT INFECTION

Le Van Tuan1, Tran Binh Duong2, Truong Nguyen Khanh Hung2, Dao Thanh Tu2,3
1 Tam Anh General Hospital, Ho Chi Minh City
2 Cho Ray Hospital
3 University of Medicine and Pharmacy at Ho Chi Minh City

Main Article Content

Abstract

Objective: To describe the application of intraoperative frozen section (FS) and analyze its association with reinfection in second-stage revision arthroplasty for patients with chronic periprosthetic hip joint infection.


Materials and Methods: A prospective case series study was conducted on 39 patients with chronic PJI who underwent two-stage revision arthroplasty at Cho Ray Hospital between January 2021 and November 2025. FS was routinely performed during the second stage using five periprosthetic tissue samples, with a negative threshold defined as <5 polymorphonuclear neutrophils per high-power field (x400).


Results: The mean age was 51.2 years, and 69.2% of patients were male. Positive bacterial cultures were identified in 74.36% of cases, with methicillin-resistant Staphylococcus aureus (MRSA) being the most common pathogen (41.03%). Positive FS results were observed in 5/39 cases (12.8%). The mean turnaround time for FS results was 40.72 ± 6.6 minutes. After a mean follow-up of 26.9 months, the success rate reached 94.9%. Positive FS results were significantly associated with postoperative reinfection (p = 0.013).


Conclusion: Intraoperative frozen section may immediately provide useful information for assessing persistent infection during second-stage reimplantation. FS should be integrated with clinical findings and serological tests to optimize surgical decision-making.

Article Details

Keywords

Frozen section; periprosthetic joint infection; two-stage revision; reinfection.

References

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