14. OUTCOMES OF LABOR INDUCTION AMONG PREMATURE OF RUPTURE OF MEMBRANE AT THE NATIONAL HOSPITAL OF OBSTETRICS AND GYNECOLOGY

Pham Van Hung1, Nguyen Quang Bac2
1 An Duc hospital of Obstetrics and Gynecoplogy
2 National Hospital of Obstetrics and Gynecology

Main Article Content

Abstract

Objective: To evaluate the effectiveness of induction of labor with oxytocin on pregnant women
with premature rupture of membranes at the National Hospital of Obstetrics and Gynecology.
Subjects and methodology: This is a descriptive study on 150 pregnant women with preterm
rupture of membranes during the period from August 2021 to August 2022 at the National Hospital
of Obstetrics and Gynecology. Results: Gestational age from 37-41 weeks accounted for 83.3%, and
from 28-31 weeks accounted for 1.3%. Cervical length at admission over 25mm accounted for 64%
after labor induction was 18.7%. After induction of labor with oxytocin, the average vaginal delivery
rate was 69.3%, and cesarean section was 30.7%. Level 3 success rate is 69.3%, and the failure rate
is 14%. The rate of amniotic infection was 3.3%, and neonatal infection was 2.7%. Conclusion:
Induction of labor with oxytocin was very effective in the subjects studied at the National Hospital of
Obstetrics and Gynecology, with meager rates of amniotic infection and neonatal infection. However,
monitoring for signs of bacteremia and neonatal sepsis needs to be more concerned with reducing
morbidity and mortality after birth.

Article Details

References

[1] Phạm Văn Khương, Nghiên cứu cách xử trí ối vỡ
non tại Bệnh viện Phụ sản trung ương năm 2008.
Luận văn tốt nghiệp chuyên khoa cấp II. Trường
Đại học Y Hà Nội.
[2] Skupski D, Preterm premature rupture of
membranes (PPROM). Journal of Perinatal
Medicine, 2019. 47(5): p. 491-492.
[3] Smith GN, Prevalence, Management, and
Outcomes of Preterm Prelabour Rupture of
the Membranes of Women in Canada. Journal
of Obstetrics and Gynaecology Canada, 2005.
27(6): p. 547-553.104
[4] Mercer BM, Antibiotic therapy for reduction of
infant morbidity after preterm premature rupture
of the membranes. A randomized controlled trial.
National Institute of Child Health and Human
Development Maternal-Fetal Medicine Units
Network. Jama, 1997. 278(12): p. 989-95.
[5] Müller H, Neurological outcome at 24 months
corrected age of prematurely born infants after
preterm premature rupture of membranes (PPROM)
of at least 7 days: a two-center experience in
Germany. The Journal of Maternal-Fetal & Neonatal
Medicine, 2020. 33(8): p. 1315-1320.
[6] Lee SM, Frequency and clinical significance of
short cervix in patients with preterm premature
rupture of membranes. PLoS One, 2017. 12(3):
p. e0174657.
[7] Mönckeberg M, Patients with acute cervical
insufficiency without intra-amniotic infection/
inflammation treated with cerclage have a good
prognosis. J Perinat Med, 2019. 47(5): p. 500-509.
[8] Mays JK, Amniocentesis for selection before
rescue cerclage. Obstet Gynecol, 2000. 95(5): p.
652-5.
[9] Ibishi VA, Isjanovska R, Malin AE, Early-onset
neonatal infection in pregnancies with prelabor
rupture of membranes in Kosovo: A major
challenge. Turk J Obstet Gynecol, 2018. 15(3):
p. 171-176.
[10] Endale T, Maternal and fetal outcomes in term
premature rupture of membrane. World J Emerg
Med, 2016. 7(2): p. 147-52.
[11] Fishman SG, Gelber SE, Evidence for the clinical
management of chorioamnionitis. Semin Fetal
Neonatal Med, 2012. 17(1): p. 46-50.
[12] Simhan HN, Canavan TP, Preterm premature
rupture of membranes: diagnosis, evaluation and
management strategies. Bjog, 2005. 112 Suppl 1:
p. 32-7.
[13] Novianesari PH, Comparison between
leukocyte esterase activity and histopathological
examination in identifying chorioamnionitis.
Case Reports in Perinatal Medicine, 2018. 7(1).
[14] Kunze M, Intrapartum management of premature
rupture of membranes: effect on cesarean delivery
rate. Obstet Gynecol, 2011. 118(6): p. 1247-1254.
[15] Goldenberg RL, Epidemiology and causes of
preterm birth. Lancet, 2008. 371(9606): p. 75-84.
[16] Beck C, Chorioamnionitis and Risk for Maternal
and Neonatal Sepsis: A Systematic Review and
Meta-analysis. Obstet Gynecol, 2021. 137(6): p.
1007-1022.
[17] Wortham JM, Chorioamnionitis and CultureConfirmed,
Early-Onset Neonatal Infections.Pediatrics, 2016. 137(1).