ACUTE TOXICITY STUDY OF SUBMERGED-FERMENTATION OF PHELLINUS LINTEUS BIOMASS POWDER
Main Article Content
Abstract
Objective: Evaluation of acute toxicity of Phellinus linteus biomass powder which obtained from submerged-fermentation in Institute of Biotechnology, VAST. Methods: Method for evaluation of drug toxicity, Medicinal Publishing House and OECD guidelines for testing of chemicals. Results and conclusions: The dose that did not cause abnormal symptoms observed in the trial was 18.0 g of sample / kg of mice. Lethal dose of 50% of experimental animals (LD50) was greater than 18.0 g of test sample / kg of mice. The results showed that mushroom biomass had low toxicity below the GHS classification threshold and did not cause toxicity to test animals.
Article Details
Keywords
Phellinus linteus, acute toxicity, submerged fermentation, mouse, biomass.
References
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