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Published: 2022-11-30
Abstract Views: 62
DOI: https://doi.org/10.52163/yhc.v63i8.521
Issue
Vol. 63 No. chuyên đề 3-HN Sản Nhi Nghệ An (2022)
Section
Articles
How to Cite
Nhi, L. N. T. ., Phong, T. Q. ., Mai, N. T. T., Thưởng, L. Q. ., Hạ, P. T. ., & Kiên, Đoàn X. . (2022). RELATIONSHIP BETWEEN SPERM DNA FRAGMENTATION INDEX AND CONVENTIONAL SEMEN PARAMETERS IN MALE PATIENTS WITH INFERTILITY. Vietnam Journal of Community Medicine, 63(chuyên đề 3-HN Sản Nhi Nghệ An). https://doi.org/10.52163/yhc.v63i8.521

RELATIONSHIP BETWEEN SPERM DNA FRAGMENTATION INDEX AND CONVENTIONAL SEMEN PARAMETERS IN MALE PATIENTS WITH INFERTILITY

Le Ngoc Tue Nhi1, Truong Quoc Phong1, Nguyen Thi Tuyet Mai2, Le Quy Thuong2, Pham Thai Ha2, Doan Xuan Kien2
1 Phu Tho Obstetrics & Pediatrics Hospital
2 Hanoi University of Science and Technology

Main Article Content

Abstract

Objectives: To determine the relationship between sperm chromatin dispersion test (SCD)
parameters (DNA fragmentation index - DFI) and conventional semen parameters in male patients
with infertility.
Subjects and methods: A cross-sectional descriptive study was performed on 150 semen
samples of male patients by masturbation at the Center for Assisted Reproduction and Andrology -
Phu Tho Obstetrics & Pediatrics Hospital. Evaluation of semen parameters according to WHO
(2021) and determination of sperm DNA fragmentation index by SCD method.
Results: A significant negative association between DFI with: Sperm density (r = -0.405,
p<0.001), Sperm Mobility (r = - 0.30 và p < 0.001), Vitality (r = - 0.31 và p < 0.001), Sperm
Morphology (r = -0.456 và p = <0.001). There is no difference in the degree of sperm
fragmentation by age, time to abstain from ejaculation, ejaculate volume, pH.
Conclusion: SCD Parameters had a significant negative association with: Sperm density,
Mobility Sperm, Vitality, Sperm Morphology. No correlation was found between DFI-SCD with:
Age, time to abstain from ejaculation, pH.

Article Details

Keywords

Halosperm, Sperm DNA fragmentation, infertile men, Sperm chromatin dispersion test.

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