Article Sidebar

Published: 2022-11-30
Abstract Views: 103
DOI: https://doi.org/10.52163/yhc.v63i8.520
Issue
Vol. 63 No. chuyên đề 3-HN Sản Nhi Nghệ An (2022)
Section
Articles
How to Cite
Ấu, V. P. ., Pha, P. M. ., & Sơn, P. V. . (2022). TREATMENT OF HYPOXIC ISCHEMIC ENCEPHALOPATHY BY APPLYING OF THERAPEUTIC HYPOTHERMIA AT CAMAU OBSTETRICS-PEDIATRIC HOSPITAL FROM 2017 TO 2022. Vietnam Journal of Community Medicine, 63(chuyên đề 3-HN Sản Nhi Nghệ An). https://doi.org/10.52163/yhc.v63i8.520

TREATMENT OF HYPOXIC ISCHEMIC ENCEPHALOPATHY BY APPLYING OF THERAPEUTIC HYPOTHERMIA AT CAMAU OBSTETRICS-PEDIATRIC HOSPITAL FROM 2017 TO 2022

Vo Phi Au1, Pham Minh Pha1, Phan Viet Son1
1 Ca Mau Hospital of Obstetrics and Pediatrics

Main Article Content

Abstract

Objective: To evaluate treatment results of neonatal hypoxic ischemic encephalopathy (HIE)
by applying of therapeutic hypothermia at Camau Obstetrics and Pediatrics Hospital from 2017 to
2022.
Method: Cross sectional. 23 HIE newborns were indicated for treatment by therapeutic
hypothermia at Camau Obstetrics and Pediatrics Hospital from 2017 to 2022.
Results: In 23 HIE newborn, male accounted for 78.3%, severe HIE accounted for 48.8%, the
average age at onset of therapeutic hypothermia was 165.0 ± 88.3 minutes; during procedure
56.5% of newborn had convulsions; 26.1% had PH < 7.2; 13.0% had heart rate less 100 beats per
min, hyperglycemia requiring insulin-therapy; 8.7% had coagulation disorders, platelets less
100,000 per microliter. The mortality rate accounted for 17.4%; Infants with psychomotor
retardation recorded at 12 months old were 20.0%; at 18 months old were 16.7%.
Conclusion: Hypothermia is significant in the treatment of moderate-severe HIE, contributing
to the reduction of mortality and cerebral sequelae.

Article Details

Keywords

Sơ sinh, bệnh não do thiếu oxy – thiếu máu cục bộ.

References

1. Akisu M, “Selective head cooling with
hypothermia suppresses the generation of
platelet-activating factor in cerebrospinal fluid
of newborn infants with perinatal asphyxia”.
Prostaglandins Leukot Essent Fatty Acids
69,pp. 45–50, 2003.
2. Bryce J, Boschi-Pinto C, Shibuya K et al.,
“WHO estimates of the causes of death in
children”, Lancet, 365(9465), pp. 1147-52,
2005.
3. Jacobs SE, “Cooling for newborns with
hypoxic ischaemic encephalopathy”, Cochrane
Database Syst Rev, 31(1):CD003311, pp. 1 –
30, 2013.
4. Li C, “Prenatal and neonatal risk factors
for perinatal arterial ischaemic stroke: a
systematic review and meta-analysis”, Eue J N
eurol, 24(8), pp. 1006-1015, 2017.
5. Lawn JE, “Lancet Neonatal Survival
Steering Team (2005), 4 million neonatal
deaths: when? Where? Why?”, Lancet.
365(9462): pp. 891-900.
6. Lin ZL, “Mild hypothermia via selective
head cooling as neuroprotective therapy in term
neonates with perinatal asphyxia: an experience
from a single neonatal intensive care unit”. J
Perinatol 26: 180–184, 2006.
7. Robertson NJ, “Therapeutic hypothermia
for birth asphyxia in low-resource settings: a
pilot randomised controlled trial”, Lancet
372(9641): 801–3, 2008.
8. Thayyil S, “WholeBody Cooling in
Neonatal Encephalopathy using Phase
Changing Material”, Arch Dis Childhood, 2010
(in press).
9. Zhou WH, “Selective head cooling with
mild systemic hypothermia after neonatal
hypoxic-ischemic encephalopathy: a
multicenter randomized controlled trial in
china”. J Pediatr 157: 367–372, 2010.