NEONATAL OUTCOMES OF INTRAUTERINE GROWTH RESTRICTION CASES FROM 37 WEEKS AT HANOI OBSTETRICS AND GYNECOLOGY HOSPITAL
Main Article Content
Abstract
Objective: To evaluate neonatal outcomes in cases of fetal growth restriction from 37 weeks of gestation at Hanoi Obstetrics and Gynecology Hospital.
Objects and Methods: A prospective cross-sectional descriptive study was conducted on 139 pregnant women at ≥37 weeks of gestation diagnosed with fetal growth restriction. Neonatal outcomes were followed up and evaluated in infants born to mothers admitted for management and pregnancy termination at Hanoi Obstetrics and Gynecology Hospital.
Results: Increasing gestational age was associated with a lower birth weight percentile (p < 0.05). The mean birth weight was 2320 ± 153.2 g. One neonatal death was recorded (0.7%), occurring in the group with a birth weight percentile below the 3rd percentile. The proportion of neonates with a 1-minute Apgar score <7 was 3.6%, while the rate at 5 minutes was 0.7%. The most common neonatal complications were respiratory distress and neonatal infection, each accounting for 6.5%. NICU admission was required in 28.1% of neonates. Abnormal umbilical artery Doppler findings were significantly associated with an increased risk of a 1-minute Apgar score <7 (p < 0.05). A cerebroplacental ratio (CPR) ≤1 was significantly associated with an increased risk of NICU admission (p < 0.05).
Conclusion: Appropriate timing of delivery in fetal growth restriction is essential to minimize adverse neonatal outcomes, including respiratory distress and neonatal mortality. The cerebroplacental ratio and umbilical artery Doppler assessment provide important clinical information for identifying fetal compromise, supporting delivery timing decisions, and prognosticating postnatal neonatal outcomes.
Article Details
Keywords
Fetal growth restriction; neonatal outcomes
References
2. Haroun Heshmat SW. Intrauterine Growth Restriction, Antomy Physiol Biochem Int J. 2017; 1(5), 001-005, DOI: 10.19080/APBIJ.2017.01.555572
3. Kady Sue M và Gardosi, Jason. Perinatal mortality and fetal growth restriction. Best Practice Research Clinical Obstetrics Gynaecology. 2004; 18(3), tr. 397-410, DOI: 10.1016/j.bpobgyn.2004.02.009
4. Thạch Thảo Đan Thanh, Bùi Chí Thương. Kết cục thai chậm tăng trưởng trong tử cung có chỉ định chấm dứt thai kỳ tại Bệnh viện Từ Dũ. Y học thành phố Hồ Chí Minh. 2017; tr. 21(1), 97-101, DOI: 10.56535/jmpm.v49i9.911
5. Unterscheider, Julia và các cộng sự. Optimizing the definition of intrauterine growth restriction: the multicenter prospective PORTO Study. American Journal Of Obstetrics Gynecology. 2013; 208(4), tr. 290. e1-290. e6, DOI: 10.1016/j.ajog.2013.02.007
6. Hasmasanu Monica G và các cộng sự. Neonatal short-term outcomes in infants with intrauterine growth restriction. Saudi Medical Journal. 2015; 36(8), tr. 947, DOI: 10.15537/smj.2015.8.11533
7. Vũ Quang Linh. Nghiên cứu về giá trị chẩn đoán thai chậm phát triển trong tử cung tại Bệnh viện Phụ sản Trung Ương trong ba năm từ 2005 – 2007, Trường Đại học Y Hà Nội. 2007.
8. Sharma Prachi và Mehta Amiya U. Study of fetomaternal implications in intrauterine growth restriction pregnancies. International Journal of Reproduction, Contraception, Obstetrics Gynecology. 2024; 13(4), tr. 895-899, DOI: https://doi.org/10.18203/2320-1770.ijrcog20240783
9. D'Agostin Martina và các cộng sự. Long-term implications of fetal growth restriction. World Journal Of Clinical Cases. 2023; 11(13), tr. 2855, DOI: 10.12998/wjcc.v11.i13.2855
10. Nguyễn Thị Bích Vân. Kết cục thai nghén của thai chậm phát triển trong tử cung tại Bệnh viện Phụ sản Trung ương từ năm 2020 đến 2023. Tạp chí Y học Cộng đồng. 2025; 66(CĐ11-NCKH), DOI: https://doi.org/10.52163/yhc.v66iCD11.2811
11. Lê Thị Kiều Trang, Huỳnh Nguyễn Khánh Trang. Kết cục thai kì ở thai chậm tăng trưởng trong tử cung từ 34 tuần nhập viện tại Bệnh viện Hùng Vường, Đại học Y dược Thành phố Hồ Chí Minh. 2017.
12. Figueras Francesc và các cộng sự. Small-for-gestational-age fetuses with normal umbilical artery Doppler have suboptimal perinatal and neurodevelopmental outcome. European Journal of Obstetrics Gynecology Reproductive Biology. 2008; 136(1), tr. 34-38, DOI: 10.1016/j.ejogrb.2007.02.016