SỰ PHÙ HỢP TRONG SỬ DỤNG THUỐC ĐIỀU TRỊ BỆNH TAY CHÂN MIỆNG

Abstract

Objective: To evaluate the appropriateness in using drugs of hand, foot and mouth disease treatment at the Children’s Hospital of Can Tho city in 2019. Subjects and methods: Retrospective cross-sectional descriptive study on 400 medical records of inpatients at Can Tho Children’s Hospital during the period from January 2019 to December 2019. Results: There was a statistically significant difference between the group of patients using the dose appropriate to the prescribed dose (P = 0.000 <0.005). Drugs with the most suitable delivery rhythm were Paracetamol, Midazolam, Diazepam, Adrenalin, Dobutamim, Immunoglobulin G, Cefuroxim with 100% as recommended. The lowest rate of used drugs compared to the recommendations was Cefotaxim (89.9%) and Ceftriaxon (83.3%). The most used oral medications: Paracetamol, Ibuprofen, Phenobarbital, Chlorpheniramine, Diazepam, Adrenalin, Dobutamim, Immunoglobulin G were suitable to the 100% recommendation. The lowest appropriate rate compared with the recommendation was Cefuroxime, which accounted for 6.7%, using the injection route in accordance with the recommendation. The more common pair of interactions was Paracetamol and Phenobabital concomitantly accounted for 90.6% of the total 149 of the recorded interactions and a lower proportion was the pair of Midazolam with Phenobabital, accounting for 9.4%. Conclusion: Most drugs with highly suitable indications for use, of which the highest were Paracetamol, Diazepam, Adrenalin, Dobutamim, Immunoglobulin G. Antibiotics had the lowest appropriate utilization rate.