THE ROLE OF PEGOS GINGIVAL MOUTHWASH IN PLAQUE CONTROL: A RANDOMIZED CONTROLLED CLINICAL TRIAL
Main Article Content
Abstract
Objective: To evaluate the adjunctive efficacy of Pegos Gingival mouthwash for dental plaque control in patients with plaque-induced gingivitis.
Methods: A double-blind, randomized controlled clinical trial was conducted in 123 participants assigned to an intervention group (Pegos Gingival) or a control group (0.9% NaCl). Plaque accumulation was assessed at baseline and at 2 and 4 weeks using the Turesky Modification of the Quigley–Hein Index (TMQHI). Between-group comparisons were performed for TMQHI category distribution and mean TMQHI scores.
Results: At week 4, the distribution of TMQHI categories (very low, low, moderate, high) was 47.6%, 31.7%, 17.5%, and 3.2% in the intervention group versus 15.0%, 53.3%, 20.0%, and 11.7% in the control group (p < 0.001). Mean TMQHI at week 4 was lower in the intervention group than in the control group (1.13 ± 0.92 vs. 1.74 ± 0.86).
Conclusion: Pegos Gingival mouthwash demonstrated an adjunctive benefit in plaque control, resulting in significantly lower plaque accumulation than 0.9% NaCl after 4 weeks.
Article Details
Keywords
dental plaque; plaque control; mouthwash; TMQHI; randomized controlled trial.
References
[2] Mawardi H.H., Elbadawi L.S., và Sonis S.T. (2015). Current understanding of the relationship between periodontal and systemic diseases. Saudi Med J, 36(2), 150–158. DOI: 10.15537/smj.2015.2.9424
[3] Al-Abdaly M.M.A.A., Alasmari A.H., Alqahtani S.J. và cộng sự. (2022). Extra-Oral Digital Panoramic Radiographic Interpretation and Clinical Findings of Stage IV Periodontitis among Some Samples Concerning Saudi/Non-Saudi Nationality. Open J Stomatol, 12(2), 42–61. DOI: 10.4236/ojst.2022.122005.
[4] Nguyễn T.T.T., Nguyễn V.Đ.Đ., Vũ M.T. và cộng sự. (2021). Hiệu quả hỗ trợ điều trị viêm lợi của dung dịch súc miệng HMU chlorhexidine 0,12%. Tạp Chí Học Việt Nam, 504(1). DOI: 10.51298/vmj.v504i1.871
[5] Turesky S., Gilmore N.D., và Glickman I. (1970). Reduced Plaque Formation by the Chloromethyl Analogue of Vitamin C. J Periodontol, 41(1), 41–43. DOI:10.1902/jop.1970.41.41.41
[6] Martínez-Hernández M., Reda B., và Hannig M. (2020). Chlorhexidine rinsing inhibits biofilm formation and causes biofilm disruption on dental enamel in situ. Clin Oral Investig, 24.DOI: 10.1007/s00784-020-03250-3
[7] Van Strydonck D.A.C., Slot D.E., Van der Velden U. và cộng sự. (2012). Effect of a chlorhexidine mouthrinse on plaque, gingival inflammation and staining in gingivitis patients: a systematic review. J Clin Periodontol, 39(11), 1042–1055.
[8] DOI: 10.1111/j.1600-051X.2012.01883.x.
[9] James P., Worthington H.V., Parnell C. và cộng sự. (2017). Chlorhexidine mouthrinse as an adjunctive treatment for gingival health. Cochrane Database Syst Rev, 3(3), CD008676. DOI: 10.1002/14651858.CD008676.pub2.
[10] Fardal O. và Turnbull R.S. (1986). A review of the literature on use of chlorhexidine in dentistry. J Am Dent Assoc 1939, 112(6), 863–869. DOI:10.14219/jada.archive.1986.0118.
[11] Vitiello F., Monterubbianesi R., Sparabombe S. và cộng sự. (2024). Use of over-the-counter mouthwashes as an additional measure in individual oral prophylaxis on adults with plaque-induced gingivitis: a double-blind, parallel, randomized controlled trial. BMC Oral Health, 24(1), 83. DOI: 10.1186/s12903-023-03779-1.