Article Sidebar

Published: 2022-09-29
Abstract Views: 228
DOI: https://doi.org/10.52163/yhc.v63i5.422
Issue
Vol. 63 No. 5 (2022)
Section
Articles
How to Cite
Trí, B. Đặng M. ., Loan, Đinh T. T. ., Thắm, N. H. ., & Thủy, N. T. . (2022). EFFECTIVENESS OF ANALGESIA WITH FENTANYL OR KETAMIN COMBINED MORPHINE OR MORPHIN ON ABDOMINAL SURGERY PATIENTS. Vietnam Journal of Community Medicine, 63(5). https://doi.org/10.52163/yhc.v63i5.422

EFFECTIVENESS OF ANALGESIA WITH FENTANYL OR KETAMIN COMBINED MORPHINE OR MORPHIN ON ABDOMINAL SURGERY PATIENTS

Bui Dang Minh Tri1, Dinh Thi Thanh Loan2, Nguyen Hong Tham3, Nguyen Thu Thuy4
1 Pham Ngoc Thach Medical University
2 Tay Do University
3 Vinh Long General Hospital
4 108 Military Central Hospital

Main Article Content

Abstract

Objective: To compare the analgesic efficacy of fentanyl, morphine in combination with ketamine
and morphine alone after abdominal surgery.
Subjects and methods: Prospective clinical, randomized and controlled study on 90 patients
undergoing elective abdominal surgery at Vinh Long General Hospital from June 2021 to June 2022.
Results: The analgesic effectiveness as lying still was similar between the three groups with the
average VAS score at all time points below 3 points. The analgesic effectiveness as moving of the
fentanyl group alone and the morphine-ketamine combination group were better than that of the
morphine alone group at the time of evaluation on day 2. The percentage of patients with pain relief
levels from satisfied or above (all over 90%), A/D ratio (all > 74%) were similar between the three
groups.
Conclusion: The analgesic effectiveness as lying still was similar between the three groups, while
the analgesic effectiveness as moving was better in the fentanyl group and in the morphine-ketamine
combination group than in the morphine alone group (day 2).

Article Details

Keywords

Abdominal surgery, fentanyl, morphine, ketamine.

References

[1] Hurley RW, Murphy JD, Wu C et al., Acute
Postoperative Pain, in Miller’s anesthesia, Miller
Editors, 2015: 2974-2997.
[2] Macintyre PE, Safety and efficacy of patientcontrolled analgesia, Br J Anaesth, 2001; 87(1):
36-46.
[3] Ballantyne JC, Postoperative patient-controlled
analgesia: meta-analyses of initial randomized
control trials, J Clin Anesth, 1993; 5(3): 182-93.
[4] Walder B, Efficacy and safety of patient-controlled
opioid analgesia for acute postoperative pain. A
quantitative systematic review, Acta Anaesthesiol
Scand, 2001; 45(7): 795-804.
[5] Hutchison R, A comparison of a fentanyl,
morphine, and hydromorphone patient-controlled
intravenous delivery for acute postoperative
analgesia: a multicentered study of opioid
induced adverse reactions, Hospital Pharmacy,
2006; 41(7): 659-663.
[6] Peng PWH, Sandler AN, A Review of the Use of
Fentanyl Analgesia in the Management of Acute
Pain in Adults, Anesthesiology, 1999; 90(2):
576-599.
[7] Ginsberg B, The influence of lockout intervals
and drug selection on patient-controlled analgesia
following gynecological surgery, Pain, 1995;
62(1): 95-100.