CLINICAL AND SUBCLINICAL CHARACTERISTICS OF PATIENTS WITH CYSTICERCOSIS IN NATIONAL INSTITUTE OF MALARIA, PARASITOLOGY AND ENTOMOLOGY, 2017 - 2020

Dang Thi Thanh1, Nguyen Quoc Dung2, Nguyen Quang Thieu1, Tran Quang Phuc1
1 National Institute of Malariology, Parasitology and Entomology
2 Viet Xo Hospital

Main Article Content

Abstract

Cysticercosis (ATSL) is a parasitic disease with a wide spectrum of clinical manifestations so it is difficult to diagnose.


Objectives: To study the clinical and subclinical characteristics of patients with ATSL.


Methods: Collecting information of 120 ALS patients treated at the National Institute of Malaria, Parasitology and Entomology during…. .


Results: The mean age was 51.23 ±11.59 years old. The highest proportion was found among the 41–50 -year age group (30.8%) and 51-60 -year age group (34.2%). The majority of the patients was male (80.0%) and female accounted for only 20%. The most common symptoms were headache (88.3%), convulsions (60.0%) followed by other symptoms such as fainting, memory loss, limb numbness... There were 5% patients with a history of defecating tapeworm proglottis and 2.5% having subcutaneous nodules. The majority of patients had a long duration of symptoms and 49.2% of them had the disease for 2 years or more. Eosinophilia was reported in 37.5% of the patients with the average proportion of eosinophils was of 4.56%. On magnetic resonance imaging of the brain, the cysts were mainly detected in the hemisphere (69.2% of patients), cortex, subcortical (50%).

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References

[1]. Ministry of Health (2004), Decision No. 1450/2004/QĐ-BYT on issuing the Guideline on diagnosing and treating Clonorchiasis, Paragonimus, Taenia solium and Cysticercosis.
[2]. Trieu HS, Study of genes, clinical and sub-clinical pathogens, treating results for Taenia spp and Taenia solium among patients in National Institute of Malariology, Parasitology and Entomology from 2007 – 2010, Medical doctor’s thesis, 2013.
[3]. Tuan PA, Dung TTK, Remarks on Prevalence of people with Taenia solium from 1992 to December 2000 (2002), Medicine of Ho Chi Minh City, 2003, 6, 1:40-45.
[4]. Tuan PA, Dung TTK, Nhi VA, Application of ELISA diagnosis technology into identifying the clinical types of Taenia solium in human, Medicine of Ho Chi Minh City, 7, Supplement No. 1: 193-198, 2003.
[5]. Binh VTL, Dung DT, Vinh HQ, et al., Human Taeniasis and Cysticercosis and Related Factors in Phu Tho Province, Northern Vietnam, Korean J Parasitol, Vol. 59, 2021, No. 4: 369-376.
[6]. Garcia HH, Nash TE, Del Brutto OH, Clinical symptoms, diagnosis, and treatment of neurocysticercosis, Lancet Neurol; 2014, 13:1202–1215.
[7]. Huang X, Wang Z, Kou J, et al., A Large Cohort of Neurocysticercosis in Shandong Province, Eastern China, 1997-2015. Vector borne and zoonotic diseases (Larchmont, N.Y.), 2019, 19(12), 901–907.
[8]. Iqbal J, Ahmad S, Al-Awadhi M, et al., A Large Case Series of Neurocysticercosis in Kuwait, a Nonendemic Arabian Gulf Country in the Middle East Region, Microorganisms, 2021, 9(6).
[9]. JeanAnne MWare, Nash TE, The Lack of Association of Eosinophilia and Neurocysticercosis at Clinical Presentation: A Retrospective Analysis of Cases Seen at the National Institutes of Health, 1985-2015. The American journal of tropical medicine and hygiene vol. 95,6 (2016): 1432-1434.
[10]. O’Connell E, Nutman T, Eosinophilia in infectious diseases. Immunol Allergy Clin North Am, 2015; 35(3):493–522.
[11]. Son HJ, Kim MJ, Jung KH, et al., Neurocysticercosis: Clinical Characteristics and Changes from 26 Years of Experience in an University Hospital in Korea. Korean J Parasitol, 2019, 57(3):265-271.
[12]. Trung DD, Praet N, Cam TD, et al., Assessing the burden of human cysticercosis in Vietnam, Tropical Medicine and International Health, 2013, 18, 3, 352 – 356.