Characteristics of dyslipidemia in patients with type 2 diabetes
Main Article Content
Abstract
Dyslipidemia is the main cause of atherosclerosis and cardiovascular diseases in patients with type 2 diabetes.
Objectives: To investigate the characteristics of lipid components and their relationship with some factors in patients with type 2 diabetes mellitus.
Subjects and methods: A cross-sectional descriptive study of 105 patients with type 2 diabetes treated at the Department of Endocrinology and Diabetes, Nghe An General freindship Hospital, from January 2021 - June 2021.
Results: The prevalence of dyslipidemia was 86.7%. Individual lipid abnormality of elevated TC, TG, LDL - C and reduced HDL-C were identified in 26.7% , 61.9%, 64.8%, and 47.6% of study subjects, respectively. The prevalence of disorder of 2 lipid components is 25.7%; disorders of 3 lipid components were 23.8% and disorder of 4 lipid componemts were 13.3%. There was a statistically significant positive correlation between waist circumference and TC (r = 0.289; p < 0.05) and TG (r = 0.238; p < 0.05). There is a positive correlation between HbA1c and TC (r = 0.246; p < 0.05), TG (r = 0.297; p < 0.05) and a statistically significant negative correlation between HbA1c and HDL - C (r = - 0.2; p < 0.05).
Conclusion: The prevalence of dyslipidemia is found in the majority of patients with type 2 diabetes. Therefore, screening and treatment of dyslipidemia is necessary to prevent cardiovascular complications in diabetic patients.
Article Details
Keywords
Lipid, HbA1c, type 2 diabetes
References
2. Vijayaraghavan K, Treatment of dyslipidemia in patients with type 2 diabetes, Lipids in Health and Disease, 2010; 9:144
3. Trien VD, Thom NV, Thuy DB, Characteristics of dyslipidemia in patients with type 2 diabetes treated in Thai Binh Preventive medicine center, Vietnam Journal of preventive medicine, 2015; Vol XXV; 8 (168): 349.
4. Chi CM, Survey on dyslipidemia and atherosclerotic indices in patients with type 2 diabetes, Vietnam journal of diabetes and endocrinology, 2018; 29: 1859-4727.
5. Huyen VTT, Huong TTT, Nghia VX, Characteristics of lipid disorders in elderly patients with type 2 diabetes mellitus, Journal of Military pharmaco - Medicine, 2014; 5: 98 – 104
6. IDF Diabetes Atlas, 9th Edition 2019.
7. Tuan LD, Hoa TTT, Nga NTP, et al., The correlation between lipid disorder and serum glucagon like peptide-1 in newly diagnosed type 2 diabetes mellitus patients with either overweight or obesity, Vietnam journal of diabetes and endocrinology, 2020; 38: 53 – 59.
8. Yanhu D, Weiguo G, Lei Z, et al., Patient characteristics related to metabolic disorders and chronic complications in type 2 diabetes mellitus patients hospitalized at the Qingdao Endocrine and Diabetes Hospital from 2006 to 2012 in China, Diabetes & Vascular Disease Research, 2017, Vol. 14(1): 24–32.
9. Shiferaw B, Tagesech Y, Abdurehman EM, Dyslipidemia and associated factors among diabetic patients attending Durame General Hospital in Southern Nations, Nationalities, and People’s Region. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 2017;10: 265–271.
10. Begum A, Irfan SR, Hoque MR, et al., Relationship between HbA1c and Lipid Profile Seen in Bangladeshi Type 2 Diabetes Mellitus Patients Attending BIRDEM Hospital: A Cross-Sectional Study, Mymensingh Med J, 2019; 28(1):91-95
11. Subashini CT, Nureslyna SB, Elizabeth G, et al., Relationship between dyslipidaemia and glycaemic status in patients with type 2 diabetes mellitus, Malaysian J Pathol, 2016; 38(2) : 123 – 130.