COMPARISION OF BLOOD PRESSURE STABILIZATION BETWEEN 6% HYDROXYETHYL STARCH 130/0.4 WITH NATRICLORUA 0,9% BEFORE EPIDURAL ANESTHESIA IN CEASAREAN SECTION

Nguyen The Loc1, Nong Thanh Tung1, Phi Van Cong1, Nguyen Van Binh1, Nguyen Lan Huong1, Nguyen Thi Nam1, Ngo Toan Anh1
1 National hospital of Obstetrics and Gyneacology

Main Article Content

Abstract

Objectives: To evaluate effect of blood pressure stabilization between 6% Hydroxyethyl starch 130/0.4 with Natriclorua 0.9% IV before epidural anesthesia in C-section.


Methodology: This is a single blind, randomized control trial among singleton pregnant women in Department of Surgery and Anesthesia, National hospital of Obtetrics and Gynecology from May 2020 to November 2020.


Results: Mean period of pre-anesthesia T10 in group 1 was 2,88 ± 0,43 vs 2,85 ± 0,70 in group 2 (p>0,05). Mean period of pre-anesthesia T10 in group 1 was 4,04 ± 0,57 vs 3,80 ± 0,72 in group 2 (p>0,05). The rate of insensitivity in both group was 100%. Value of systolic, diastolic and mean of blood pressure was elevated compare to those before infusion (p<0,01). Min of systolic blood pressure in group 1 was lower than that of group 2 (p<0,05), group 1 systolic BP remained higher than that of group 2. Total amount of infusion in group 2 was significantly higher than that of group 1 (p<0,01).


Conclusion: 6% HES 130/0.4 intravenous before epidural anesthesia was an effective method to prevent hypotension. Therefore, this method should be used largely especially in C-section.

Article Details

References

1. Phan DV, Physio-pharmaceutical anesthesia. Physio-pharmacy: Hanoi Medical Publisher; 1998. p. 145-51.
2. Ngoc NH, Research on subarachnoid anesthesia by using low dose bupivacaine in combination with fentanyl in C-section, Hanoi Medical university; 2003.
3. Cong BQ, Research on effect of epidural anesthesia by using low dose Marcain and Fentanyl in C-section, Hanoi Medical university; 2003.
4. Loi DV, Study of combination of Bupivacain and Morphin or Fentanyl in epidural anesthesia in C-section and post surgery pain relief, Hanoi medical university; 2007.
5. Abouleish E, Rawal N, Fallon K et al., Combined intrathecal morphine and bupivacaine for cesarean section, Anesth Analg, 1988;67(4):370-4.
6. Mercier FJ, Diemunsch P, Ducloy-Bouthors AS, et al., 6% Hydroxyethyl starch (130/0.4) vs Ringer's lactate preloading before spinal anaesthesia for Caesarean delivery: the randomized, double-blind, multicentre CAESAR trial, Br J Anaesth, 2014; 113(3):459-67.
7. Lewis SR, Pritchard MW, Evans DJ et al., Colloids versus crystalloids for fluid resuscitation in critically ill people, Cochrane Database Syst Rev, 2018; 8(8):CD000567-CD.
8. Sigurjonsson J, Hedman D, Bansch P et al., Comparison of dextran and albumin on blood coagulation in patients undergoing major gynaecological surgery, Perioper Med (Lond), 2018;7:21.
9. Loubert C, Hallworth S, Fernando R et al., Does the baricity of bupivacaine influence intrathecal spread in the prolonged sitting position before elective cesarean delivery? A prospective randomized controlled study, Anesth Analg, 2011; 113(4):811-7.
10. Helill SE, Sahile WA, Abdo RA et al., The effects of isobaric and hyperbaric bupivacaine on maternal hemodynamic changes post spinal anesthesia for elective cesarean delivery: A prospective cohort study, PLoS One, 2019; 14(12):e0226030.