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Published: 2024-12-02
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DOI: https://doi.org/10.52163/yhc.v65iCD11.1745
Issue
Vol. 65 No. CĐ11 - Liên chi hội CTCH TP.HCM
Section
Articles
How to Cite
Nhân, D. T., Quang, N. T., Thanh, L. Q., & Khoa, T. Đăng. (2024). 10. CLINICAL CASE REPORTS OF PROSTHETIC JOINT INFECTIONS TREATED WITH MOBILE ANTIBIOTIC-IMPREGNATED CEMENT SPACERS. Vietnam Journal of Community Medicine, 65(CĐ11 - Liên chi hội CTCH TP.HCM). https://doi.org/10.52163/yhc.v65iCD11.1745

10. CLINICAL CASE REPORTS OF PROSTHETIC JOINT INFECTIONS TREATED WITH MOBILE ANTIBIOTIC-IMPREGNATED CEMENT SPACERS

Duong Thanh Nhan1, Nguyen Thanh Quang1, Lam Quoc Thanh1, Tran Dang Khoa1
1 Hospital for Traumatology and Orthopaedics

Main Article Content

Abstract

Objective: This study assesses the clinical efficacy of utilizing a custom-manufactured articulating antibiotic-loaded cement spacer in the management of periprosthetic joint infections (PJI), as observed in cases treated at the Ho Chi Minh City Orthopedic Trauma Hospital from 2022 to 2024.


Methods: A case series involving four patients with confirmed PJI, including two cases of prosthetic knee infection and two cases involving hip prosthesis infections, were managed with an articulating antibiotic-impregnated cement spacer. This approach aimed to maintain joint functionality while enabling eradication of infection prior to second-stage reimplantation. Outcomes were compared to those associated with static spacers that lack articulating functionality.


Results: All patients demonstrated favorable clinical outcomes, with effective infection resolution and absence of severe complications over the observation period. Enhanced postoperative range of motion and overall improvement in quality of life were documented, with rapid analgesic response and early ambulation.


Conclusion: The application of a custom-manufactured articulating antibiotic-loaded cement spacer is a feasible, cost-effective, and clinically advantageous intervention for PJI management. It provides effective infection control while preserving joint mobility, thereby optimizing conditions for successful reimplantation in a two-stage revision arthroplasty. This approach is especially beneficial for resource-limited healthcare settings.

Article Details

Keywords

periprosthetic joint infection, antibiotic-loaded cement, articulating spacer, twostage revision arthroplasty, orthopedic surgery

References

[1] Anagnostakos K. Therapeutic Use of Antibiotic-loaded Bone Cement in the Treatment of Hip and Knee Joint Infections. J Bone Jt Infect. 2017;2(1):29–37.
[2] Barrack RL. Rush pin technique for temporary antibiotic-impregnated cement prosthesis for infected total hip arthroplasty. J Arthroplasty.
2002;17:600-3.
[3] Durbhakula SM, Czajka J, Fuchs MD, Uhl RL. Spacer endoprosthesis for the treatment of infected total hip arthroplasty. J Arthroplasty. 2004;19:760-7.
[4] Fehring TK, Odum S, Calton TF, Mason JB. Articulating Versus Static Spacers in Revision Total Knee Arthroplasty for Sepsis. 2000;380:9-16.
[5] Hammerich K, Pollack J, Hasse AF, et al. The Inverse Spacer-A Novel, Safe, and Cost-Effective Approach in Routine Procedures for Revision Knee Arthroplasty. Journal of clinical medicine. 2021;10(5).