29. TÌNH HÌNH XƠ HOÁ GAN VÀ HIỆU QUẢ CAN THIỆP KIẾN THỨC VÀ THỰC HÀNH Ở NAM GIỚI TRUNG NIÊN SỬ DỤNG RƯỢU

Abstract

Objective: (1) To determine the prevalence of liver fibrosis in middle–aged men who consume alcohol; (2) To assess the effectiveness of knowledge and practice interventions in improving liver fibrosis in middle–aged male alcohol users.

Subject and method: A cross–sectional descriptive study with an uncontrolled intervention was conducted on 513 middle–aged male alcohol users who came Military Hospital 121 for a routine health check-up from April 2022 to March 2023.

Results: The prevalence of liver fibrosis was 29.3%. After the intervention, the rate of achieving general knowledge increased from 18.4% to 82.3%, achieving general practice increased from 4.8% to 98.6%, and achieving both knowledge and practice increased from 0.0% to 81.6%. The prevalence of liver fibrosis decreased to 73.5%, with a statistically significant difference (p<0.001). Initial liver fibrosis stage ≥ F2 and failure to achieve both knowledge and practice post–intervention were associated with no improvement in liver fibrosis stage.

Conclusion: The prevalence of liver fibrosis was nearly one–third among middle–aged male alcohol users. Knowledge and practice interventions during examination and treatment adherence partially improved liver fibrosis; however, the effectiveness was limited in patients with fibrosis stage F2 and above.