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Published: 2024-07-31
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DOI: https://doi.org/10.52163/yhc.v65iCD6.1370
Issue
Vol. 65 No. CĐ 6 - Bệnh viện Lê Văn Thịnh
Section
Articles
How to Cite
Lâm, Q. T. ., Trân, L. B., Tài, N. D., & Giao, H. (2024). 15. NO RESPONSE TO HBV VACCINATION- SOME PRACTICAL ISSUES. Vietnam Journal of Community Medicine, 65(CĐ 6 - Bệnh viện Lê Văn Thịnh). https://doi.org/10.52163/yhc.v65iCD6.1370

15. NO RESPONSE TO HBV VACCINATION- SOME PRACTICAL ISSUES

Quach Thanh Lam1, Le Bao Tran1, Nguyen Duy Tai2, Huynh Giao1,2
1 Ho Chi Minh University of Medicine and Pharmacy
2 Le Van Thinh Hospital

Main Article Content

Abstract

Objective: The study aims to investigate the causes and management of cases where certain individuals do not develop protective responses after receiving the hepatitis B vaccine (HBV), which is commonly observed in clinical settings.


Method: The study was conducted by searching data from two databases: PubMed and domestic studies on immune responses after hepatitis B vaccination.


Results: Literature review shows that the hepatitis B vaccine is safe and effective. However, the immune response decreases after the age of 40 and in individuals with immuno-compromised conditions. Additionally, individuals with occult HBV infection also have very poor responses to the HBV vaccine.


Conclusion: It is recommended in practice, besides the HBsAg test, to also perform the anti-HBc test before vaccination to identify these cases for better counseling

Article Details

Keywords

HBV (Hepatitis B Virus); HBsAg (Hepatitis B surface Antigen); Anti-HBs (Hepatitis B surface Antibody); Anti-HBc (Antibody against the core of Hepatitis B virus); occult HBV infection; no respond to HBV vaccination

References

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