41. EVALUATION OF COMPLEMENTARY EFFECTS OF DIEBETES TREATMENT AND CANCER CELL INHIBITION USING A FERMENTED PRODUCT DERIVED FROM CASHEW APPLE AND NONI FRUITS

Phung Thi Kim Hue1,2, Do Thi Thao1,3, Tran Van Loc1,4, Nguyen Cong Danh5, Tran Gia Hung5, Luong Minh Khang2, To Tu Hien2, Nguyen Tuan Khoi2, Le Tri Vien1
1 Institute of Health Research and Educational Development in Central Highlands
2 Hung Vuong Gifted High School
3 Institute of Biotechnology, Vietnam Academy of Science and Technology
4 Institute of Chemistry, Vietnam Academy of Science and Technology
5 A Sanh High School

Main Article Content

Abstract

Every year, approximately 5.6 million tons of cashew apples have been discarded in the local region
of Ia Grai District, Gia Lai Province. In addition to their sugar and mineral content, cashew apples
contain biochemical active compounds which confer various health benefits thanks to their
antioxidative, anti-inflammatory and anti-cancer properties. Noni fruits, unfortunately, encounter a
comparable outcome. Both fruits are currently considered waste products, resulting in large wastage.


Objective: The objective of this study is to evaluate the hypoglycemic and anti-proliferative cancer
cell effects of a fermented product (NCF) derived from cashew apples and noni fruits.


Method: In the study, blood glucose levels were measured using Sivalingam's (2013) methods and
Mosmann's (1983) method was employed to assess the anti-cancer properties,…


Results: The results demonstrated that the NCF contains a substantial amount of antioxidants, which
can directly or indirectly contribute to reducing blood glucose levels and inhibit cancer cell growth.
Moreover, NCF significantly lowered blood glucose levels in mice and enhanced catalase activity in
the mice’s liver (p<0.05). Notably, NCF exhibited significant anticancer effects against liver and
cervical cancer (p<0.05).


Conclusion: These findings underscore the importance of utilizing overlooked plant by products
(Cashew apple and Noni fruits) to develop functional beverages that can potentially contribute to
human health protection.

Article Details

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