26. CLINICAL FEATURES AND RISK FACTORS OF PATIENTS WITH INVASIVE PULMONARY ASPERGILLOSIS AT NATIONAL LUNG HOSPITAL FROM 2019 TO 2020

Khuat Thi Luong1, Nguyen Thi Bich Ngoc1, Mai Manh Tu1
1 National Lung Hospital

Main Article Content

Abstract

Objective: To describe the clinical features and risk factors of patients with invasive pulmonary Aspergillosis treated at the National Lung Hospital.


Methods: Retrospective descriptive study on 47 patients with invasive pulmonary Aspergillosis, treated at the National Lung Hospital from January 2019 to December 2020.


Results: The average age was 54 ± 14 years old, 59.6% were 18-60 years olds, male/female was 2/1. The most common reasons for being hospitalized are breathless (48.9%) and fever (17%). However, the earliest symptoms of the disease appear 1-3 weeks before admission: Fever (40.4%) and phlegm cough (40.4%). 30/47 (63.8%) patients had host factors for EORTC/ MSG, mainly hematological malignancies (34%) and long-term corticosteroid use (23.4%). Other co-morbidities are diabetes (34%), hypertension (10.6%), and chronic hepatitis (14.9%).


Conclusion: Clinical features of invasive pulmonary Aspergillosis are multiform and non-specific, you have to think about fungal infection in patients with risk factors and have persistent respiratory symptoms that do not improve with common treatment.

Article Details

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