26. ĐẶC ĐIỂM LÂM SÀNG VÀ YẾU TỐ NGUY CƠ CỦA BỆNH NHÂN NẤM PHỔI ASPERGILLUS XÂM LẤN TẠI BỆNH VIỆN PHỔI TRUNG ƯƠNG GIAI ĐOẠN 2019-2020

Abstract

Objective: To describe the clinical features and risk factors of patients with invasive pulmonary Aspergillosis treated at the National Lung Hospital.

Methods: Retrospective descriptive study on 47 patients with invasive pulmonary Aspergillosis, treated at the National Lung Hospital from January 2019 to December 2020.

Results: The average age was 54 ± 14 years old, 59.6% were 18-60 years olds, male/female was 2/1. The most common reasons for being hospitalized are breathless (48.9%) and fever (17%). However, the earliest symptoms of the disease appear 1-3 weeks before admission: Fever (40.4%) and phlegm cough (40.4%). 30/47 (63.8%) patients had host factors for EORTC/ MSG, mainly hematological malignancies (34%) and long-term corticosteroid use (23.4%). Other co-morbidities are diabetes (34%), hypertension (10.6%), and chronic hepatitis (14.9%).

Conclusion: Clinical features of invasive pulmonary Aspergillosis are multiform and non-specific, you have to think about fungal infection in patients with risk factors and have persistent respiratory symptoms that do not improve with common treatment.