EARLY OUTCOMES OF SURGICAL TREATMENT FOR AORTIC VALVE STENOSIS AT HANOI MEDICAL UNIVERSITY HOSPITAL

Nguyen Quang Huy1, Vu Ngoc Tu1, Le Van Hung2, Dang Van Khanh2
1 Hanoi Medical University
2 Hanoi Medical University Hospital

Main Article Content

Abstract

1.Objective: To evaluate the clinical and paraclinical characteristics as well as the early surgical outcomes of patients with aortic valve stenosis treated at Hanoi Medical University Hospital during the period 2021–2024.



  1. Methods: A descriptive study was conducted on patients diagnosed with aortic valve stenosis who underwent surgery at Hanoi Medical University Hospital from January 2021 to December 2024.


3.Results: The study included 40 patients with a mean age of 63.7 ± 8.2 years; males accounted for 67.5%. The main symptom was chest pain (65%). NYHA class II before surgery was observed in 85%. All patients (100%) had a systolic murmur at the aortic valve area. Preoperative echocardiography showed left ventricular enlargement with LVM(g) 240.2 ± 75.2, and most patients had preserved left ventricular function, with 80% having EF >50%. All patients presented with severe aortic valve stenosis and ascending aortic dilatation, with a mean transvalvular gradient of 62.5 ± 16.1 and ascending aortic diameter of 40.5 ± 5.2 mm. A bicuspid aortic valve abnormality was found in 35 patients (87.5%). Surgical procedures included 17.5% with ascending aortic replacement, 40% with ascending aortic wrapping, and 7.5% with mitral valve repair using an annuloplasty ring. Postoperatively, 95% of patients were discharged with good outcomes; one patient died due to intraoperative Stanford type A aortic dissection leading to multiorgan failure, and one required reoperation for sternal reconstruction due to sternal dehiscence.


4.Conclusion: Aortic valve stenosis is predominantly observed in the elderly population, manifesting with a heterogeneous spectrum of cardiac symptoms, ascending aortic involvement, and comorbidity-related conditions. Surgical management primarily consists of aortic valve replacement combined with appropriate intervention on the ascending aorta, achieving a high rate of procedural success.

Article Details

References

[1] Đỗ Doãn Lợi. Hẹp van động mạch chủ. Trong: Bài giảng tim mạch học. Hội tim mạch học Việt Nam; 2014. tr 1–20.
[2] Stephan PJ, Henry AC III, Hebeler RF Jr, Whiddon L, Roberts WC. Comparison of age, gender, number of aortic valve cusps, concomitant coronary artery bypass grafting, and magnitude of left ventricular-systemic arterial peak systolic gradient in adults having aortic valve replacement for isolated aortic valve stenosis. Am J Cardiol. 1997 Jan 15;79(2):166–72. doi:10.1016/S0002-9149(96)00705-9
[3] Man D.L., Zipes., Douglas P., et al. Braunwald’s heart disease: a textbook of cardiovascular medicine. 10th a.b. Philadelphia: Elsevier; 2015. 1452–1454 tr.
[4] Everett RJ, Newby DE, Jabbour A, Fayad ZA, Dweck MR. The Role of Imaging in Aortic Valve Disease. Curr Cardiovasc Imaging Rep. 2016 Jun 7;9(7):21. doi:10.1007/s12410-016-9383-z.
[5] Behnoush AH, Khalaji A, Naderi N, Ashraf H, von Haehling S. ACC/AHA/HFSA 2022 and ESC 2021 guidelines on heart failure comparison. ESC Heart Fail. 2022 Dec 2;10(3):1531–1544. doi:10.1002/ehf2.14255.
[6] Nishimura RA, Otto CM, Bonow RO, Carabello BA, Erwin JP, Fleisher LA, Jneid H, Mack MJ, McLeod CJ, O’Gara PT, Rigolin VH, Sundt TM, Thompson A. 2017 AHA/ACC Focused Update of the 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2017;135(25):e1159–e1195. doi:10.1161/CIR.0000000000000503
[7] Wang K, Zhang H, Jia B. Current surgical strategies and techniques of aortic valve diseases in children. Transl Pediatr. 2018;7(2):83–90. doi:10.21037/tp.2018.02.03
[8] Cribier A, Eltchaninoff H, Bash A, Borenstein N, Tron C, Bauer F, Derumeaux G, Anselme F, Laborde F, Leon MB. Percutaneous transcatheter implantation of an aortic valve prosthesis for calcific aortic stenosis: first human case description. Circulation. 2002;106(24):3006–3008. doi:10.1161/01.CIR.0000047200.36165.B8.
[9] Calle-Valda CM, Aguilar R, Benedicto A, Sarraj A, Monguio E, Munoz D, De Antonio N, Reyes G. Outcomes of aortic valve replacement according to surgical approach in intermediate and low risk patients: a propensity score analysis. Heart Lung Circ. 2018;27(7):885–892. doi:10.1016/j.hlc.2017.08.010..
[10] Đinh Huỳnh Linh. Nghiên cứu ứng dụng kỹ thuật thay van động mạch chủ qua đường ống thông điều trị hẹp khít van động mạch chủ. Luận án tiến sĩ Y học. Trường Đại học Y Hà Nội; 2020.