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Đã xuất bản: 2024-12-12
Số lượt xem tóm tắt: 18
Số lượt xem PDF: 8
DOI: https://doi.org/10.52163/yhc.v65iCD12.1833
Số xuất bản
Tập 65 Số CĐ 12 - Bệnh viện Thủ Đức
Chuyên mục
Bài báo khoa học
Cách trích dẫn
Minh, C. T. Ánh, Dung, N. T. P., Trinh, N. V., Hiền, P. T. T., Nhi, N. T. N., Hà, N. T., Tùng, H., & Phương, N. T. L. (2024). 23. TỔNG QUAN HỆ THỐNG VỀ HIỆU QUẢ - AN TOÀN VÀ BẰNG CHỨNG KINH TẾ DƯỢC CỦA THUỐC RITUXIMAB TIÊM DƯỚI DA SO VỚI RITUXIMAB TIÊM TRUYỀN TĨNH MẠCH Ở NGƯỜI BỆNH U LYMPHO KHÔNG HODGKIN. Tạp Chí Y học Cộng đồng, 65(CĐ 12 - Bệnh viện Thủ Đức). https://doi.org/10.52163/yhc.v65iCD12.1833

23. TỔNG QUAN HỆ THỐNG VỀ HIỆU QUẢ - AN TOÀN VÀ BẰNG CHỨNG KINH TẾ DƯỢC CỦA THUỐC RITUXIMAB TIÊM DƯỚI DA SO VỚI RITUXIMAB TIÊM TRUYỀN TĨNH MẠCH Ở NGƯỜI BỆNH U LYMPHO KHÔNG HODGKIN

Châu Thị Ánh Minh1, Nguyễn Thị Phương Dung2, Ngô Việt Trinh2, Phạm Thị Thu Hiền2, Ngô Thị Ngọc Nhi2, Nguyễn Thị Hà2, Hoàng Tùng2, Nguyễn Thị Lan Phương2
1 Trung tâm DI & ADR Khu vực Thành phố Hồ Chí Minh
2 Trường Đại học Khoa học Sức khỏe, Đại học Quốc gia Thành phố Hồ Chí Minh

Nội dung chính của bài viết

Tóm tắt

Objective: This study synthesized evidence on the clinical and pharmacoeconomic aspects of subcutaneous (SC) versus intravenous (IV) rituximab for non-Hodgkin lymphoma (NHL).


Methods: The systematic review was performed according to the PRISMA statement. The search was processed on PubMed, Scopus, and Embase until February 26, 2023. Studies reported the safety, efficacy, or cost-effectiveness of rituximab SC compared with rituximab IV among NHL patients were eligible for the analysis.


Results: For evidence of efficacy and safety, three RCTs and one case-control study were included in the systematic review. The results showed no statistically significant difference between rituximab SC and rituximab IV in the safety or efficacy indicators for the treatment of NHL. In addition, results from eight pharmacoeconomic studies suggested that rituximab SC significantly helped shorten the time for healthcare workers as well as patients, and saved related costs compared to rituximab IV for the treatment of NHL.


Conclusions: Rituximab SC and rituximab IV were proved to be not different in terms of safety and efficacy for the treatment of NHL. This review also indicated that compared to rituximab IV, rituximab SC saved time and costs for the treatment of NHL in a hospital setting.

Chi tiết bài viết

Từ khóa

Rituximab, u lympho không Hodgkin, hiệu quả, an toàn, tổng quan hệ thống

Tài liệu tham khảo

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