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Published: 2024-03-08
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DOI: https://doi.org/10.52163/yhc.v65i2.946
Issue
Vol. 65 No. 2
Section
Articles
How to Cite
Hoàn, N. D. ., Tuyến, P. B. ., Nam, N. T. ., & Liên, N. T. . (2024). 27. THE EFFECT OF INHIBITING BENIGN PROSTATIC HYPERPLASIA OF “TLT-BCA” PILLS ON EXPERIMENT. Vietnam Journal of Community Medicine, 65(2). https://doi.org/10.52163/yhc.v65i2.946

27. THE EFFECT OF INHIBITING BENIGN PROSTATIC HYPERPLASIA OF “TLT-BCA” PILLS ON EXPERIMENT

Nguyen Duy Hoan1, Pham Ba Tuyen2, Nguyen Truong Nam3, Nguyen Thi Lien4
1 Vietnam University Of Traditional Medicine & Pharmacy
2 Traditional Medicine Hospital, Ministry of Public Security
3 Phenikaa University
4 Rang Dong light source and vacuum flask joint stock Company

Main Article Content

Abstract

Objectives: To evaluate the effect of “TLT-BCA” pills on inhibiting benign prostatic hyperplasia induced by testosterone propionate (TP) in Wistar rats.


Subjects and methods: Wistar rats were injected subcutaneously with TP at a dose of 3mg/kg/24h or with sesame oil (physiological control group), and given “TLT-BCA” (treatment 1 and 2 groups), Dutasteride (reference group) or physiological saline (physiological control and pathological control groups) for 28 consecutive days.


Results: “TLT-BCA” pills at dose 700mg/kg/24h and 2100mg/kg/24h reduced prostate weight, decreased MDA concentration in both blood and prostate tissue of rats (p < 0.01 compared to the pathology).


Conclusions: “TLT-BCA” pills have reduced prostate weight on the model of benign prostatic hyperplasia in Wistar rats. The mechanism of action may be involved in the antioxidant effects.

Article Details

Keywords

Benign prostatic hyperplasia, wistar rat, “TLT-BCA”.

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