7. MULTIMORBIDITY BURDEN AND ITS ASSOCIATION WITH FRAILTY IN OSTEOPOROTIC OLDER ADULTS
Main Article Content
Abstract
Objective: To evaluate the prevalence of multimorbidity and the association between multimorbidity and frailty in older adults with osteoporosis.
Method: A cross-sectional descriptive study was conducted on 296 older adults treated at the Department of Rheumatology, the Department of Neurosurgery, Rheumatology clinic, University Medical Center Ho Chi Minh city.
Results: The prevalence of multimorbidity among participants was 43,2% (128/296). The common comorbidities included osteoarthritis and hypertension. The multimorbidity group was more likely to have higher mean age, history of vertebral fracture, ADL and IADL dependence, and frailty than the non-multimorbidity group. However, the multimorbidity group was less likely to be physically active than the other group. In the univariate logistic regression model, multimorbidity was associated with frailty, but the association was insignificant when the regression models were adjusted for age.
Conclusion: Older adults with osteoporosis had a relatively high multimorbidity burden of 43,2%. Multimorbidity was associated with frailty in the univariate model but this association did not persist when the models were adjusted for age.
Article Details
Keywords
Multimorbidity, frailty, osteoporosis, older adults.
References
Epidemiol Rev, 35, 2013, 75-83.
[2] Rizzuto D, Melis RJF, Angleman S et al., Effect
of Chronic Diseases and Multimorbidity on
Survival and Functioning in Elderly Adults. J
Am Geriatr Soc, 65(5), 2017, 1056-60.
[3] Bliuc D, Tran T, Chen W et al., The association
between multimorbidity and osteoporosis
investigation and treatment in high-risk fracture
patients in Australia: A prospective cohort study.
PLoS Med, 20(1), 2023, e1004142.
[4] Luo Y, Chen Y, Wang K et al., Associations
between multimorbidity and frailty transitions
among older Americans, J Cachexia Sarcopenia
Muscle, 14(2), 2023, 1075-82.
[5] Chen Y, Shi L, Zheng X et al., Patterns and
Determinants of Multimorbidity in Older Adults:
Study in Health-Ecological Perspective. Int J
Environ Res Public Health, 19(24), 2022.
[6] Barcelos A, Lopes DG, Canhao H et al.,
Multimorbidity is associated with fragility
fractures in women 50 years and older: A
nationwide cross-sectional study. Bone
Rep,15:101139, 2021.
[7] Rodrigues LP, de Oliveira Rezende AT,
Delpino FM et al., Association between
multimorbidity and hospitalization in older
adults: systematic review and meta-analysis.
Age Ageing, 51(7), 2022.
[8] Gao C, Xu Y, Li L et al., Prevalence of
osteoporotic vertebral fracture among
community-dwelling elderly in Shanghai. Chin
Med J (Engl), 132(14):1749-51, 2019.
[9] Christofoletti M, Sandreschi PF, Quadros EN
et al., Physical activity and sedentary behavior
as multimorbidity discriminators among elderly
Brazilians: a cross-sectional study. Sao Paulo
Med J, 139(4):372-9, 2021.
[10] Vetrano DL, Palmer K, Marengoni A et al.,
Frailty and Multimorbidity: A Systematic
Review and Meta-analysis. J Gerontol A Biol Sci
Med Sci, 74(5):659-66, 2019.