RARE CLINICAL CASE REPORT: HETEROTOPIC PREGNANCY FOLLOWING IN VITRO FERTILIZATION
Main Article Content
Abstract
Heterotopic pregnancy is the simultaneous occurrence of an intrauterine pregnancy and an ectopic pregnancy. It is a rare condition in natural conception but has shown a marked increase with the widespread use of assisted reproductive technologies. Interstitial ectopic pregnancy is a particularly dangerous form due to the risk of delayed rupture and massive hemorrhage. We report a rare case of heterotopic pregnancy consisting of a viable intrauterine pregnancy and a right interstitial tubal pregnancy following in vitro fertilization in a patient with a history of right salpingectomy. The patient was diagnosed early by ultrasonography and promptly managed with laparoscopic surgery, allowing preservation of the intrauterine pregnancy. The pregnancy progressed favorably and was completed by term cesarean delivery with a healthy newborn. This case highlights the importance of early diagnosis of heterotopic pregnancy (a viable intrauterine pregnancy and an interstitial tubal pregnancy) in patients who conceive after assisted reproductive techniques, even in those with a history of salpingectomy, to enable timely surgical management and achieve favorable outcomes for both the mother and the intrauterine pregnancy.
Article Details
Keywords
Heterotopic pregnancy; Interstitial pregnancy; In vitro fertilization; Ectopic pregnancy.
References
2. E.A. Reece, R.H. Petrie, M.F. Sirmans, M. Finster, W.D. Todd, Combined intrauterine
and extrauterine gestations: a review, Am. J. Obstet. Gynecol. 146 (3) (1983) 323–330
3. J. Tal, S. Haddad, N. Gordon, I. Timor-tritsch, Heterotopic pregnancy after ovulation induction and assisted reproductive technologies: a literature review from 1971 to 1993, Fertil. Steril. 66 (1) (1996) 1–12.
4. McKeown C, et al. Heterotopic pregnancy following spontaneous conception. Ir Med J. 2023.
5. Liu Y, et al. Abdominal heterotopic pregnancy after in vitro fertilization and embryo transfer: A case report. 2022.
6. Nguyen KP, et al. Spontaneous heterotopic pregnancy: Diagnosis and management. Cureus/PMC. 2022.
7. Krishnamoorthy K, et al. The incidence of ectopic/heterotopic pregnancies after assisted reproductive technology. Fertil Steril Rep. 2021.
8. Ozgur K, Isikoglu M. Cornual heterotopic pregnancy: conservative treatment with transvaginal embryo reduction. Arch Gynecol Obstet 2005; 271: 73-5.
9. Tulandi T, Al-Jaroudi D. Interstitial pregnancy: results generated from the Society of Reproductive Surgeons Registry. Obstet Gynecol. 2004;103(1):47–50.
10. Timor-Tritsch IE, Monteagudo A, Matera C, Veit CR. Sonographic evolution of cornual pregnancies treated without surgery. Obstet Gynecol 1992; 79: 1044-9.