EVALUATION OF INDUCED LABOR USING OXYTOCIN INFUSION IN FULL-TERM PREGNANT WOMEN AT LUC YEN MEDICAL CENTER IN 2025

Nguyen Ngoc Minh Hai1, Nguyen Son Huy2, Tran Van Luu3, Hoang Tien Dat4, Ma Thi Thuy Tra4, Tran Trung Thanh4, Nguyen Thi Bich Van1,2
1 Hanoi Medical University Hospital
2 Hanoi Medical University
3 National Endocrinology Hospital
4 Luc Yen Regional Health Center

Main Article Content

Abstract

Background and Objectives: Induction of labor is essential when spontaneous labor fails, reducing maternal-fetal risks. Intravenous oxytocin is the most common method. This study evaluated outcomes of oxytocin-induced labor and associated factors at Luc Yen Medical Center in 2025.


Methods: A prospective case series followed 104 full-term pregnant women receiving oxytocin infusion at the Department of Reproductive and Obstetric Health, Luc Yen Medical Center, from April to October 2025. Success was defined as vaginal delivery (including forceps/vacuum) within 24 hours of starting oxytocin; failure as cesarean conversion due to arrested cervical dilation, fetal distress, non-engagement, or hyperstimulation. Data were analyzed using SPSS 16.0 with χ² tests and logistic regression to identify associated factors.


Results: Mean maternal age was 27.2 ± 4.2 years; 88.5% had intact membranes on admission. The most common indications were weak/infrequent uterine contractions (48.1%), prolonged labor (37.5%), and premature rupture of membranes (14.4%). The mean Bishop score was 6.18 ± 0.13. The success rate was 73.1%. Among 26.9% failures, 50% were due to arrested cervical dilation, 35.7% to fetal distress, and 14.3% to non-engagement. All newborns had Apgar scores ≥ 7 at minutes 1 and 5; no severe maternal complications (uterine rupture, severe postpartum hemorrhage, ICU admission) were recorded in the study sample. A Bishop score > 6 was significantly associated with success (p < 0.001).


Conclusion: Oxytocin-induced labor at Luc Yen Medical Center achieved a 73.1% success rate, with no notable adverse neonatal outcomes recorded in the study sample.

Article Details

References

1. Cheng YW, Hopkins LM, Caughey AB. How long is too long: Does a prolonged second stage of labor in nulliparous women affect maternal and neonatal outcomes? Am J Obstet Gynecol. 2004;191(3):933-938. doi:10.1016/j.ajog.2004.05.044
2. Landy HJ, Laughon SK, Bailit JL, et al. Characteristics associated with severe perineal and cervical lacerations during vaginal delivery. Obstet Gynecol. 2011;117(3):627-635. doi:10.1097/AOG.0b013e31820afaf2
3. Grobman WA, Rice MM, Reddy UM, et al. Labor Induction versus Expectant Management in Low-Risk Nulliparous Women. N Engl J Med. 2018;379(6):513-523. doi:10.1056/NEJMoa1800566
4. Middleton P, Shepherd E, Morris J, Crowther CA, Gomersall JC. Induction of labour at or beyond 37 weeks’ gestation. Cochrane Database Syst Rev. 2020;7(7):CD004945. doi:10.1002/14651858.CD004945.pub5
5. Lueth GD, Kebede A, Medhanyie AA. Prevalence, outcomes and associated factors of labor induction among women delivered at public hospitals of MEKELLE town-(a hospital based cross sectional study). BMC Pregnancy Childbirth. 2020;20(1):203. doi:10.1186/s12884-020-02862-7
6. Phạm Hồng Yến, Phạm Mỹ Hoài. 34. KẾT QUẢ ĐẺ CHỈ HUY TĨNH MẠCH BẰNG OXYTOCIN Ở THAI PHỤ ĐỦ THÁNG TẠI BỆNH VIỆN A THÁI NGUYÊN. Tạp Chí Học Cộng Đồng. 2025;66(2). doi:10.52163/yhc.v66i2.2091
7. Reddy UM, Sandoval GJ, Tita ATN, et al. Oxytocin regimen used for induction of labor and pregnancy outcomes. Am J Obstet Gynecol MFM. 2024;6(12):101508. doi:10.1016/j.ajogmf.2024.101508
8. Hoàng Thị Ngọc Trâm. 20. Một số yếu tố liên quan đến kết quả của đẻ chỉ huy tĩnh mạch bằng oxytocin ở thai đủ tháng. Tạp Chí Nghiên Cứu Học. 2025;192(7):178-186. doi:10.52852/tcncyh.v192i7.3511
9. Sanchez-Ramos L, Levine LD, Sciscione AC, et al. Methods for the induction of labor: efficacy and safety. Am J Obstet Gynecol. 2024;230(3S):S669-S695. doi:10.1016/j.ajog.2023.02.009
10. Dương Thị Khao Ry, Dương Mỹ Linh, Nguyễn Hữu Dự, Bùi Quang Nghĩa, Trần Trọng Nhân. KẾT QUẢ KHỞI PHÁT CHUYỂN DẠ BẰNG OXYTOCIN VÀ DINOPROSTONE TRÊN THAI TRÊN 37 TUẦN. Tạp Chí Dược Học Cần Thơ. 2024;(76):159-165. doi:10.58490/ctump.2024i76.2674
11. Chang TA, Li YR, Ding DC. Oxytocin and vaginal dinoprostone in labor induction: A systematic review and meta-analysis. Int J Gynecol Obstet. 2024;166(2):626-638. doi:10.1002/ijgo.15443
12. Trung tâm Y tế Lục Yên. Báo Cáo Công Tác Năm 2023, 2024 Của Khoa CSSKSS và Phụ Sản.
13. Nguyễn Văn Huỳnh, Trần Thị Quỳnh Chi, Nguyễn Thị Kim Ngân, Tạ Thị Mỹ Hạnh, Nguyễn Công Điệp. Kết quả đẻ chỉ huy bằng truyền Oxyticin tĩnh mạch tại Viện Y học biển năm 2019. Viện Y học biển; 2019. Accessed January 22, 2026. http://lib.vinimam.org.vn:8080/handle/123456789/167