LEFT VENTRICULAR LONGITUDINAL STRAIN INDICES ON 2D SPECKLE-TRACKING ECHOCARDIOGRAPHY IN PATIENTS WITH MITRAL STENOSIS
Main Article Content
Abstract
Mitral stenosis is a common heart valve disease in Vietnam, characterized by the narrowing of the mitral valve orifice as a result of rheumatic valve damage. Early detection of left ventricular dysfunction in asymptomatic mitral stenosis patients is crucial. Myocardial speckle tracking echocardiography (STE) is a novel technique that can provide additional information beyond conventional ultrasound parameters and may assist physicians in assessing, risk-stratifying, and optimizing the timing of intervention or surgery for asymptomatic patients with severe mitral stenosis. The objective of the study: "To investigate the left ventricular longitudinal strain index (GLS) using 2D speckle tracking echocardiography in patients with mitral stenosis." The study revealed that the average left ventricular longitudinal strain value in the mitral stenosis patient group was significantly lower than the normal threshold (–21%), even though the left ventricular ejection fraction (EF) remained preserved. This impairment was unevenly distributed across regions, with a notable reduction observed in the basal and mid-left ventricular segments, while the apical region remained relatively preserved.
Article Details
Keywords
mitral stenosis, speckle tracking echocardiography.
References
2.Negi PC, Kandoria A, Asotra S, et al. Gender differences in the epidemiology of Rheumatic Fever/Rheumatic heart disease (RF/RHD) patient population of hill state of northern India; 9 years prospective hospital based, HP-RHD registry. Indian Heart J. 2020;72(6):552-556. doi:10.1016/j.ihj.2020.09.011.
3.29. Lu Q, Lv J, Li Z, et al. Cardiovascular Risk Factors in Patients with Valvular Heart Disease: A Nationwide Observational Cohort Study. Int J Gen Med. 2024;Volume 17:5651-5664. doi:10.2147/IJGM.S498982.
4.Žvirblytė R, Merkytė I, Tamulėnaitė E, et al. Right Ventricle Mechanics and Function during Stress in Patients with Asymptomatic Primary Moderate to Severe Mitral Regurgitation and Preserved Left Ventricular Ejection Fraction. Medicina (Mex). 2020;56(6):303. doi:10.3390/ medicina56060303.
5.Cvijic M. Application of strain echocardiography in valvular heart diseases. Anatol J Cardiol. Published online 2020. doi:10.14744/ AnatolJCardiol.2020.09694.
6.Thomas JD, Edvardsen T, Abraham T, et al. Clinical Applications of Strain Echocardiography: A Clinical Consensus Statement From the American Society of Echocardiography Developed in Collaboration With the European Association of Cardiovascular Imaging of the European Society of Cardiology. J Am Soc Echocardiogr. Published online August 2025:S0894731725003955. doi:10.1016/j.echo. 2025. 07.007.
7.Nguyễn T.T.H., Hoàng T.H.M. “Nghiên cứu hình thái và diện tích lỗ van hai lá bằng phương pháp siêu âm tim 3d qua thực quản ở bệnh nhân hẹp hai lá khít có chỉ định nong van bằng bóng qua da”. Tạp Chí Học Việt Nam. 2023;525(2). doi:10.51298/vmj.v525i2.5169.
8.Baumgartner H, Hung J, Bermejo J, et al. Echocardiographic Assessment of Valve Stenosis: EAE/ASE Recommendations for Clinical Practice. J Am Soc Echocardiogr. 2009;22(1):1-23. doi:10.1016/j.echo.2008.11.029.
9.Otto CM, Nishimura RA, Bonow RO, et al. 2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease. J Am Coll Cardiol. 2021;77(4):e25-e197. doi:10.1016/j.jacc.2020.11.018.
10.Pandian NG, Kim JK, Arias-Godinez JA, et al. Recommendations for the Use of Echocardiography in the Evaluation of Rheumatic Heart Disease: A Report from the American Society of Echocardiography. J Am Soc Echocardiogr. 2023;36(1):3-28. doi:10.1016/j.echo.2022.10.009.
11.Sengupta SP, Amaki M, Bansal M, et al. Effects of Percutaneous Balloon Mitral Valvuloplasty on Left Ventricular Deformation in Patients with Isolated Severe Mitral Stenosis: A Speckle-Tracking Strain Echocardiographic Study. J Am Soc Echocardiogr. 2014;27(6):639-647. doi:10.1016/j.echo.2014.01.024.
12.Mehrabi-Pari S, Nayebirad S, Shafiee A, et al. Segmental and global longitudinal strain measurement by 2-dimensional speckle tracking echocardiography in severe rheumatic mitral stenosis. BMC Cardiovasc Disord. 2023;23(1):584. doi:10.1186/s12872-023-03624-x.