CLINICAL AND PARACLINICAL CHARACTERISTICS OF ACUTE CALCULOUS CHOLANGITIS AT NGUYEN TRI PHUONG HOSPITAL
Main Article Content
Abstract
Objective: To describe the clinical and paraclinical characteristics of patients with acute calculous cholangitis at Nguyen Tri Phuong Hospital
Methods: A descriptive case-series study was conducted, retrospectively reviewing the medical records of 133 patients with acute calculous cholangitis admitted and treated at the General Surgery Department from January 2023 to February 2025. Data were analyzed using Stata, presented as frequencies, percentages, medians, and interquartile ranges.
Results: The median age of the study group was 66 (53–77) years; females accounted for 63.9%. Common comorbidities included hypertension (44.4%) and diabetes mellitus (29.3%). Abdominal pain (96.2%), fever (60.9%), and jaundice (36.8%) were the main symptoms. The median WBC was 13.8 G/L, CRP was 36.7 mg/L, and total bilirubin was 43.2 µmol/L. On ultrasound, intrahepatic bile duct stones were present in 75.9%. Among positive cultures, E. coli was the most common bacterium (40.3%).
Conclusion: Patients with acute calculous cholangitis were mainly elderly females with comorbidities, presenting with typical clinical and paraclinical features of infection and biliary obstruction.
Article Details
Keywords
Acute cholangitis; Gallstones; Clinical characteristics; Paraclinical characteristics; E. coli.
References
2. Nguyen Cao Cuong, Tran Vinh Hung, Ngo Viet Thi va cs. Results of emergency treatment for cute calculous cholangitis . y hoc Thanh pho Ho Chi Minh 2018, 22(2):443–449.
3. Ngo Thi Hoai, Nguyen Lam Tung, Tran Van Thanh va cs . Results of emergency endoscopic retrograde cholangiopancreatography for acute cholangitis due to common bile duct stones in elderly patients. Journal of 108-Clinical Medicine and Phamarcy 2025.
4. Virgile J, Marathi R: Cholangitis. Treasure Island (FL). StatPearls Publishing; 2025.
5. Huang S, Zhou Y, Liang Y, Ye S, Zhu A, Li J, Bai X, Yue C, Feng Y: Machine-learning-derived online prediction models of outcomes for patients with cholelithiasis-induced acute cholangitis: development and validation in two retrospective cohorts. eClinicalMedicine 2024, 76.
6. Lavillegrand J-R, Mercier-Des-Rochettes E, Baron E et al. Acute cholangitis in intensive care units: clinical, biological, microbiological spectrum and risk factors for mortality: a multicenter study. Critical Care 2021, 25:1-8.
7. LA RRP, Hernández López C, Sanchez Torralba D et al. Microbiology of acute cholangitis and cholecystitis and their antimicrobial susceptibility. 2025.
8. Nguyen Thi Hue, Nguyen Thi Huyen Trang, Nguyen Anh Tuan, va cs. Delayed endoscopic retrograde cholangiopancreatography: a game-changer for acute cholangitis patients in a resource-limited setting. Therapeutic Advances in Gastroenterology 2025, 18:17562848251329868.
9. Gomi H, Takada T, Hwang TL, Akazawa K, Mori R et al. Updated comprehensive epidemiology, microbiology, and outcomes among patients with acute cholangitis. Journal of Hepato‐Biliary‐Pancreatic Sciences 2017, 24(6):310-318.