17. EVALUATING THE EFFECT OF SEVOFLURANE VERSUS DESFLURANE ON RECOVERY QUALITY IN PATIENTS UNDERGOING FLEXIBLE URETEROSCOPIC LITHOTRIPSY SURGERY

Dao Thi Huyen Trang1,2, Vu Hoang Phuong3,4, Tran Hong Duc1, Nguyen Van Chung1, Nguyen Thuy Trang1
1 Hanoi Medical University Hospital
2 Hanoi Medical University
3 Bệnh viện Đại học Y Hà Nội
4 Đại học Y Hà Nội

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Abstract

Objective: To evaluate the quality of recovery in patients maintained with Sevoflurane and Desflurane anesthesia during flexible ureteroscopic lithotripsy surgery, based on the QoR-15 score.


Methods: A prospective observational cohort study was conducted on 60 patients undergoing flexible ureteroscopic lithotripsy at Hanoi Medical University Hospital in 2025. Patients were equally divided into two groups (n = 30 each), matched for age and sex, and maintained with either Sevoflurane or Desflurane anesthesia.


Results: The mean time to full recovery was significantly shorter in the Desflurane group (10.96 ± 8.13 minutes) compared to the Sevoflurane group (16.44 ± 4.02 minutes, p = 0.004). Extubation time was also shorter in the Desflurane group (10.96 ± 8.13 minutes) versus the Sevoflurane group (16.44 ± 4.02 minutes, p = 0.079). Both groups achieved high total QoR-15 scores (> 130), indicating excellent postoperative recovery quality. Preoperatively, the Desflurane group had a higher QoR-15 score (140.0 ± 14.9) than the Sevoflurane group (132.2 ± 14.9, p = 0.078). Postoperatively, the Desflurane group showed a slight improvement (141.6 ± 12.3), whereas the Sevoflurane group showed a mild decrease (131.2 ± 9.6), with the difference being statistically significant (p = 0.003).


Conclusion: Both Desflurane and Sevoflurane provide good recovery quality in patients undergoing flexible ureteroscopic lithotripsy. However, Desflurane demonstrates advantages with faster recovery, earlier extubation, and improved postoperative recovery quality.

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References

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