28. APPLICATION OF STEM CELL THERAPY IN PROMOTING YOUTHFULNESS AND HEALTHY AGING
Main Article Content
Abstract
Mesenchymal stem cells (MSCs) are defined as residual stem cells in most adult organs, specifically adipose tissue (ASC or ADSC). ADSCs have been identified in the underlying tissue, which plays an important role in repairing and regenerating the skin through a variety of proven mechanisms. These involve different skin and address disadvantages or limitations in conventional treatments.
Article Details
Keywords
ADSC, regenerating the skin, regenerative medicine.
References
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[3] Lombardi F, Palumbo PA-O, Augello FR, Cifone MA-O, Cinque B, Giuliani MA-O. Secretome of Adipose Tissue-Derived Stem Cells (ASCs) as a Novel Trend in Chronic Non-Healing Wounds: An Overview of Experimental In Vitro and In Vivo Studies and Methodological Variables. LID - 10.3390/ijms20153721 [doi] LID - 3721. Int J Mol Sci 2019, 20(15): 3721.
[4] Qin Z, Balimunkwe RM, Quan T. Age-related reduction of dermal fibroblast size upregulates multiple matrix metalloproteinases as observed in aged human skin in vivo. Br J Dermatol 2017, 177(5): 1337-48.
[5] Patel S, Maheshwari A, Chandra A. Biomarkers for wound healing and their evaluation. J Wound Care, 2016, 25(1): 46-55.
[6] McIntosh KR. Evaluation of cellular and humoral immune responses to allogeneic adipose-derived stem/stromal cells. Methods Mol Biol, 2011, 702: 133-50.
[7] Moon KC, Chung HY, Han SK, Jeong SH, Dhong ES. Possibility of Injecting Adipose-Derived Stromal Vascular Fraction Cells to Accelerate Microcirculation in Ischemic Diabetic Feet: A Pilot Study. Int J Stem Cells 2019, 12(1): 107-13.
[8] Klar AS, Güven S, Biedermann T, Luginbühl J, Böttcher-Haberzeth S, Meuli-Simmen C, et al. Tissue-engineered dermo-epidermal skin grafts prevascularized with adipose-derived cells. Biomaterials, 2014, 35(19): 5065-78.
[9] Idkowiak-Baldys JA-OX, Santhanam U, Buchanan SM, Pfaff KL, Rubin LA-OX, Lyga J. Growth differentiation factor 11 (GDF11) has pronounced effects on skin biology. PLoS One, 2019, 14(6): e0218035.
[10] Argentati C, Morena F, Bazzucchi M, Armentano I, Emiliani C, Martino S. Adipose Stem Cell Translational Applications: From Bench-to-Bedside. LID - 10.3390/ijms19113475 [doi] LID - 3475. Int J Mol Sci, 2018, 19(11): 3475.