10. EVALUATION OF THE VALUE OF CRP COMPARED TO BISAP IN PREDICTING SEVERITY AND MORTALITY IN ACUTE PANCREATITIS PATIENTS
Main Article Content
Abstract
Objectives: To determine CRP levels and BISAP scores in patients with acute pancreatitis; To assess the prognostic value of CRP compared to BISAP in predicting the severity and necrosis of acute pancreatitis.
Subjects and methods: A cross-sectional study was conducted on 100 acute pancreatitis patients who were monitored and treated at Cho Ray Hospital from December 2021 to August 2022.
Results: The mean CRP levels at admission and after 48 hours were 231.6 ± 134.9 and 201.1 ± 102.0 (mg/L), respectively (p < 0.001). The BISAP score was 2.11 ± 0.96 in the severe acute pancreatitis group and 1.1 ± 0.91 in the non-severe group (p < 0.001). CRP at admission (cut-off 328 mg/L) had a prognostic value for severe acute pancreatitis and necrosis with an AUC of 0.72 (p < 0.05). CRP after 48 hours (cut-off 210 mg/L) had a prognostic value for severe acute pancreatitis with an AUC of 0.689 (p = 0.012) but no prognostic value for necrotizing acute pancreatitis. BISAP showed moderate predictive value for severe acute pancreatitis and necrotizing acute pancreatitis with AUCs of 0.771 (p < 0.001) and 0.742 (p < 0.0001), respectively.
Conclusions: CRP has value in predicting the severity of acute pancreatitis, making it suitable for rapid assessment of the patient’s condition and progression to make appropriate and timely treatment decisions.
Article Details
Keywords
BISAP, CRP, acute pancreatitis, severity, death
References
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