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Published: 2025-01-24
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DOI: https://doi.org/10.52163/yhc.v66iCD1.2024
Issue
Vol. 66 No. CĐ1
Section
Articles
How to Cite
Phương, P. T., Lượng, V. H. ., & Hiền, Đỗ T. T. (2025). 49. THE PREVALENCE OF THYROID DISEASE IN PATIENTS WITH VITILIGO AT NATIONAL HOSPITAL OF DERMATOLOGY AND VENEREOLOGY. Vietnam Journal of Community Medicine, 66(CĐ1). https://doi.org/10.52163/yhc.v66iCD1.2024

49. THE PREVALENCE OF THYROID DISEASE IN PATIENTS WITH VITILIGO AT NATIONAL HOSPITAL OF DERMATOLOGY AND VENEREOLOGY

Pham Thi Phuong1, Vu Huy Luong2, Do Thi Thu Hien2
1 Hanoi Medical University
2 National Hospital of Dermatology and Venereology

Main Article Content

Abstract

Objectives: To determine the prevalence of thyroid disease in patients with vitiligo at National Hospital of Dermatology and Venereology.


Materials and methods: We performed cross-sectional study on 318 patients diagnosed with vitiligo at National Hospital of Dermatology and Venereology from November 2023 to June 2024. Serum samples from patients were collected and tested for TSH, FT3, FT4, TRAb, Anti-TPO. Ultrasound was used to evaluate thyroid morphology. The patients with abnormal test results were sent to endocrinologist to confirm the diagnosis of  thyroid disease.


Results: Of the 318 patients, 36 (11.3%) patients had thyroid dysfunction including  hyperthyroidism (3.4%) and hypothyroidism (7.9%). The prevalence of thyroid disease was 22%, of which autoimmune thyroid disease accounted for 8.2%, thyroid nodule accounted for 12.9% and thyroid cancer accounted for 0.9%. TRAb and Anti-TPO positivity rates were 3.1% and 17.3%.


Conclusion: The study results suggested that screening for thyroid disease should be recommended in patients with vitiligo.

Article Details

Keywords

Vitiligo, thyroid disease, autoimmune thyroid disease, TRAb, Anti-TPO

References

[1] Taïeb A, Picardo M, Clinical practice, Vitiligo, N Engl J Med, 2009, 360 (2): 160-169, doi:10.1056/NEJMcp0804388.
[2] Krüger C, Schallreuter K.U, A review of the worldwide prevalence of vitiligo in children/adolescents and adults, Int J Dermatol, 2012, 51 (10): 1206-1212, doi:10.1111/j.1365-4632.2011.05377.x.
[3] Ezzedine K, Lim H.W, Suzuki T et al, Revised classification/nomenclature of vitiligo and related issues: the Vitiligo Global Issues Consensus Conference, Pigment Cell Melanoma Res, 2012, 25 (3): E1-13, doi:10.1111/j.1755-148X.2012.00997.x.
[4] Picardo M, Dell’Anna M.L, Ezzedine K et al, Vitiligo, Nat Rev Dis Primers, 2015, 1: 15011, doi:10.1038/nrdp.2015.11.
[5] Vrijman C, Kroon M.W, Limpens J et al, The prevalence of thyroid disease in patients with vitiligo: a systematic review, Br J Dermatol, 2012, 167 (6): 1224-1235, doi:10.1111/j.1365-2133.2012.11198.x.
[6] Baldini E, Odorisio T, Sorrenti S et al, Vitiligo and Autoimmune Thyroid Disorders, Frontiers in Endocrinology, 2017, 8, doi:10.3389/fendo.2017.00290.
[7] Bae J.M, Lee J.H, Yun J.S, Han B, Han T.Y, Vitiligo and overt thyroid diseases: A nationwide population-based study in Korea, J Am Acad Dermatol, 2017, 76 (5): 871-878, doi:10.1016/j.jaad.2016.12.034.
[8] Fan K.C, Yang T.H, Huang Y.C, Vitiligo and thyroid disease: a systematic review and meta-analysis, Eur J Dermatol, 2018, 28 (6): 750-763, doi:10.1684/ejd.2018.3449.
[9] Nguyễn Thái Minh Hảo, Đỗ Thị Thu Hiền, Hiệu quả điều trị bạch biến thể khu trú bằng bôi tacrolimus kết hợp chiếu đèn excimer, TC DLH VN, 2022, (35): 37-44, doi:10.56320/tcdlhvn.v35i.3.
[10] Đỗ Thị Hồng Nhung, Đỗ Thị Thu Hiền, Trần Hậu Khang, Hiệu quả điều trị bệnh bạch biến bằng chiếu UVB dải hẹp 311nm, Tạp chí Y học Việt Nam, 2017, 461 (1): 100-104.
[11] Nguyễn Thị Thanh Huyền, Nguyễn Trọng Hào, Bệnh tuyến giáp tự miễn và các yếu tố liên quan trên bệnh nhân bạch biến tại Bệnh viện Da liễu thành phố Hồ Chí Minh, TC DLH VN, 2022, (35): 28-36, doi:10.56320/tcdlhvn.v35i.2.
[12] Chauhan P.S, Sharma H, Dhattarwal N et al, Characteristics of Vitiligo in Children and Adolescents, Skinmed, 2020, 18 (5): 278-285.
[13] Gopal K.V.T, Rao G.R, Kumar Y.H, Increased prevalence of thyroid dysfunction and diabetes mellitus in Indian vitiligo patients: A case-control study, Indian Dermatol Online J, 2014, 5 (4): 456-460, doi:10.4103/2229-5178.142493.
[14] Kroon M.W, Joore I.C.K.W, Wind B.S et al, Low yield of routine screening for thyroid dysfunction in asymptomatic patients with vitiligo, Br J Dermatol, 2012, 166 (3): 532-538, doi:10.1111/j.1365-2133.2011.10717.x.
[15] Yang Y, Lin X, Fu W, Luo X, Kang K, An approach to the correlation between vitiligo and autoimmune thyroiditis in Chinese children, Clin Exp Dermatol, 2010, 35 (7): 706-710,doi:10.1111/j.1365-2230.2009.03671.x.
[16] Trần Viết Thắng, Tiếp cận chẩn đoán và điều trị bướu giáp nhân, Thời sự y học, Published online, 2014, 19-22.
[17] Antonelli A, Ferrari S.M, Corrado A, Di Domenicantonio A, Fallahi P, Autoimmune thyroid disorders, Autoimmun Rev, 2015, 14 (2): 174-180, doi:10.1016/j.autrev.2014.10.016.