27. THE USE OF COMBINATION THERAPY IN THE TREATMENT OF HEART FAILURE IN PATIENTS WITH REDUCED EJECTION FRACTION ACCORDING TO ESC 2021 GUIDELINES

Bui Xuan Khai1,2, Le Anh Khoa1, Mai Tuan Anh1, Lam Tri Dung1, Pham Bao Duy1, Nguyen Le Dang Khoa1
1 University of Health Sciences, Vietnam National University at Ho Chi Minh City
2 Thong Nhat Hospital

Main Article Content

Abstract

Background: The treatment of heart failure with reduced ejection fraction in Vietnam is of great concern, not only reflected in the increased incidence and prevalence but also in the issue of using drug combinations in treatment, this problem, however, becomes more concerning when the European Heart Association recently announced an additional group of drugs that have the ability to improve mortality prognosis in patients with heart failure with reduced ejection fraction [1]. The study conducted a survey on the combination of all four drugs in the treatment of heart failure with reduced ejection fraction at Thong Nhat Hospital from July 2023 to April 2024


Objective: Determine the proportion of heart failure patients with reduced EF who are using all medication groups as recommended by the 2021 European Society of Cardiology guidelines.


Methods: Our cross-sectional study was conducted on 87 patients with stable heart failure and reduced EF currently being treated at the cardiology department and clinic of Thong Nhat Hospital from July 2023 to April 2024.


Results: The proportion of heart failure patients with reduced EF who are treated with all four medication groups is 40.2%. The main reasons include patients having relative contraindications to the medication groups, patient adherence, and economic issues.


Conclusion: The rate of non-adherence among patients is high, thus it is necessary to develop health education communication programs, implement measures to encourage people to participate in health insurance, and increase the use of full treatment once contraindications are resolved.

Article Details

References

[1] Theresa A. McDonagh, Marco Metra, et al (2021). 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. European Heart Journal.
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