11. MULTIFOCAL OSTEOSARCOMA: CASE REPORT AND LITERATURE REVIEW

Bui Hoang Lac1, Le Van Tho2, Le Uy Phuong2, Nguyen Phu2, Le Chi Dung2
1 Traumatology and Orthopedics Hospital, HCMC
2 Hospital for Traumatology and Orthopaedics

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Abstract

Multifocal osteosarcoma or osteosarcomatosis is a rare pathological condition, characterized by two or more in the skeleton, either synchronous or metachronous, without visceral metastasis. We report a case of synchronous multifocal osteosarcoma treated at the Department of Orthopaedic Diseases and Oncology, Ho Chi Minh City Orthopaedic and Trauma Hospital.

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References

[1] Agrawal M., Patil A., James T., et al. Multifocal Osteosarcoma: Multiple Primaries or Metastases? A Report of Rare Case and Review of
Literature. Journal of Orthopaedic Case Reports 2020: 10(8): 97-100. Doi: 10.13107/jocr. 2020.v10.i 08.1878.
[2] Buzzoni R., Torre SD., Cortinovis D., et al. Case report of synchronous multicentric osteosarcoma and review of the literature: the importance of
autopsy for diagnosis. Tumori. 2005;91(1):90-2. Doi: 10.1177/030089160509100119.
[3] Amstutz HC. Multiple Osteogenic Sarcomata-Metastatic or Multicentric? Report of Two Cases and Review of Literature. Cancer 1969; 24: 923-931. Doi:10.1002/1097-0142(196911).
[4] Mahoney. JP., Spanier SS., Morris JL., et al. Multifocal Osteosarcoma: A Case Report with Review of the Literature. Cancer 1979;44: 1897-1907. Doi:10.1002/1097-0142(197911).
[5] Gotta J., Bochennek K., Klingebiel T., et al. Metachronous Osteosarcoma, A Differential Diagnosis to be Considered in Children with Osteosarcoma: A Review of Literature and a Case from Our Center. J Pediatr Hematol Oncol 2023; 45:105–110.Doi: 10.1097/MPH.0000000000002560.
[6] Setiawati R., Lay ES., Testini V., et al. Case Report. Advance MR evaluation of synchronous multifocal osteosarcoma with pathologic fracture. BJR Case Rep 2021; 7: 20210015. doi.org/10.1259/bjrcr.20210015.
[7] Gavane S., Price AP., Magnan H., et al. Multifocal Osteosarcoma Unusual Presentation and Imaging Findings. Clin Nucl Med 2017;42: e202-e206. Doi: 10.1097/RLU.0000000000001560.
[8] Corradi D., Wenger DE., Bertoni F., et al. Multicentric Osteosarcoma Clinicopathologic and Radiographic Study of 56 Cases. Am J Clin Pathol 2011;136: 799-807 799.Doi: 1309/AJCP0V0OATKCNAZP.
[9] Bacci G., Fabbri., Balladelli A., et al. Treatment and prognosis for synchronous multifocal osteosarcoma in 42 patients. J Bone Joint Surg [Br] 2006;88-B:1071-5. Doi:10.1302/0301-620X.88B8. 17809
[10] Bulut HI., Kanay E., Anarat FB., et al. Synchronous multifocal osteosarcoma: Report of 4 cases and literature review. Surgery Case Reports: Advances and Techniques 3 (2024) 100062. Doi.org/10.1016/j.sycrs.2024.100062.