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Published: 2024-12-12
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DOI: https://doi.org/10.52163/yhc.v65i13.1722
Issue
Vol. 65 No. Tiếng Anh
Section
Articles
How to Cite
Thao, N. M., & Doanh, L. H. (2024). 1. COMBINATION OF TRADITIONAL CO2 LASER AND PULSE DOSES ITRACONAZOLE IN PRIMARY TOTAL DYSTROPHIC ONYCHOMYCOSIS (TDO) TREATMENT: A CASE REPORT. Vietnam Journal of Community Medicine, 65(Tiếng Anh). https://doi.org/10.52163/yhc.v65i13.1722

1. COMBINATION OF TRADITIONAL CO2 LASER AND PULSE DOSES ITRACONAZOLE IN PRIMARY TOTAL DYSTROPHIC ONYCHOMYCOSIS (TDO) TREATMENT: A CASE REPORT

Ngo Minh Thao1, Le Huu Doanh2
1 National Hospital of Dermato-Venereology
2 Hanoi Medical University

Main Article Content

Abstract

Onychomycosis is one of the most common nail diseases. Treatment of onychomycosis, mainly moderate to severe, can be very challenging, expensive and time consuming. Compared with topical and oral therapies, laser treatment offers a more promising modality for the treatment of severe or resistant cases. To enhance the effect, the combination of oral itraconazole pulse doses with mechanical removal of the affected part of the nail plate by using ablative CO2 laser are investigated. Here, we report a total dystrophic onychomycosis case successfully treated with traditional CO 2 laser and pulse doses itraconazole. This suggests the potential of conventional ablative CO 2 laser in the treatment of severe onychomycosis.

Article Details

Keywords

Onychomycosis, CO2 laser, ablative, oral itraconazole, pulse doses, intermittent dosing

References

[1] Gasser J., Pagani E., Vittadello F., al e. Frequency, type and treatment of fungal pathogens in toenail onychomycosis in the central alpine region of South Tyrol, northern Italy: a 10-year retrospective study from 2004 to 2013. Mycoses. 2016;59(12):760-764.
[2] Lipner S.R., R.K. S. Onychomycosis: clinical overview and diagnosis. J Am Acad Dermatol. 2019;80(4):835-851.
[3] Drake L.A., Pattrick D.L., Fleckman P., al e. The impact of onychomycosis on quality of life: Development of an international onychomycosisspecific questionnaire to measure patients quality of life. J Am Acad Dermatol. 2000;41(2):189-196.
[4] Gupta A.K., Daigle D., J.L. C. The role of biofilms in onychomycosis. J Am Acad Dermatol. 2016;74(6):1241-1246.
[5] Ma W, Si C, Zhou B, al e. Laser treatment for onychomycosis. Medicine. 2019;98(48).
[6] Ameen M., Lear J.T., Madan V., al e. British Association of Dermatologists' guidelines for the management of onychomycosis 2014. British
Journal of Dermatology. 2014;171:937-958.
[7] J.F. L. The observation of efficacy of 26 cases of CO2 laser treatment for onychomycosis. Chin J Mycol. 2008;3:289-291.
[8] Yang Y, Liu H, Yang RY, al e. The observation of efficacy of Ultrapulse CO2 fractional laser treatment for onychomycosis. Chin J Dermatol. 2015:526-530.
[9] Cheng YR, Wang CY, Cao LF, al e. Clinical observation of CO2 laser treatment for onychomycosis. Chin J Dermatovenereol. 1997:53-54.
[10] Xu J, Zhuo FL, Zhang RN, al e. The progress in laser treatment for onychomycosis. Chin J Laser Med Surg. 2013:41-44.