10. ASSESSMENT OF ANXIETY, DEPRESSION AND STRESS IN CANCER PATIENTS AT THONG NHAT HOSPITAL

Hoang Thi Tuyet1, Ha Thi Theu1, Nguyen Thi Hong1, Hoang Ngoc Van1
1 Thong Nhat Hospital

Main Article Content

Abstract

Objectives: To assess the level and the relation of anxiety, depression and stress in cancer patient at Thong Nhat hospital.


Subject and method: A cross-sectional study in cancer patients admitted to Oncology Department at Thong Nhat hospital from December 1, 2020 to May 31, 2021.


Results: The proportion of cancer patients with depression, anxiety and stress was high. Nearly two-third (69.7%) of cancer patients had moderate or higher level of depression, more than half (56.8%) cancer patients had moderate or higher anxiety level and 50.30% cancer patienst were moderate and high level of stress. Most of cancer patients’ demographic factors were not associated with depression, anxiety and stress among cancer patients, but there are factors including cancer patients’ surgical status, type of cancer and pain level which were significantly associated with the depression score, anxiety score, and stress score of patients (p < 0.05). There were a statistically significant relationship between depression, anxiety, and stress with correlation coefficients of 0.848, 0.89 and 0.894, respectively.


Conclusion: The result shows that levels of anxiety, depression and stress in cancer patients are relatively high. The main finding found that factors including surgical status, type of cancer, and pain level which associated with depression score, anxiety score and stress score of cancer patients, however, and more research is needed into the reasons for patients' anxiety, depression and stress. This study provides primary source for further interventional researches among cancer patients to improve the quality of life for patients in the near future.

Article Details

References

[1] World Health Organization (WHO), “Cancer,” 2018. [Online]. Available: https://www.who.int/health-topics/cancer#tab=tab_1. [Accessed Dec.10, 2020].
[2] World Health Organization (WHO), “Viet Nam: Cancer country profiles 2014,” 2014. [Online]. Available: http://www.who.int/cancer/country-profiles/vnm_en.pdf. [Accessed Dec. 10, 2020].
[3] H. R. Smith, “Depression in cancer patients: Pathogenesis, implications and treatment (review),” Oncol. Lett., vol. 9, no. 4, pp. 1509-1514, 2015, doi: 10.3892/ol.2015.2944.
[4] K. Tsaras et al., “Assessment of depression and anxiety in breast cancer patients: Prevalence and associated factors,” Asian Pacific J. Cancer Prev., vol. 19, no. 6, pp. 1661-1669, 2018, doi: 10.22034/APJCP.2018.19.6.1661.
[5] K. M. Brintzenhofe-Szoc, T. T. Levin, Y. Li, D.W. Kissane, and J. R. Zabora, “Mixed anxiety/depression symptoms in a large cancer cohort: Prevalence by cancer type,” Psychosomatics, vol. 50, no. 4, pp. 383-391, 2009, doi: 10.1176/appi.psy.50.4.383.
[6] J. Walker et al., “Prevalence, associations, and adequacy of treatment of major depression in patients with cancer: A cross-sectional analysis
of routinely collected clinical data,” The Lancet Psychiatry, vol. 1, no. 5, pp. 343-350, 2014, doi: 10.1016/S2215-0366(14)70313-X.
[7] C. G. Ng, S. Mohamed, K. Kaur, A. H. Sulaiman, N. Z. Zainal, and N. A. Taib, “Perceived distress and its association with depression and anxiety in breast cancer patients,” PLoS One, vol. 12, no. 3, pp. 1-10, 2017, doi: 10.1371/journal.pone.0172975.
[8] WHO, “Mental health of older adults,” 2017. [Online]. Available: https://www.who.int/en/news-room/fact-sheets/detail/mental-health-ofolder-adults. [Accessed Dec. 10, 2020].
[9] G. Polonia, Analysis of sample size in consumer surveys, Nguyen Tat Thanh University, Ho Chi Minh, 2013.
[10] N. H. Minh, “Sampling method and sample size calculation in health science research” Ha Noi, May 2020. [Online]. Available: http://comau.tk. [Accessed Jun. 07, 2021].
[11] K. U. A. Mehnert, “Psychological co-morbidity and health-related quality of life and its association with awareness, utilization and need for psychosocial support in a cancer register based sample of long-term breast cancer survivors,” J Psychosom, vol. 64, pp. 383-391, 2008.
[12] D. A. Nelson, T. T. Tan, A. B. Rabson, D. Anderson, K. Degenhardt, and E. White, “Hypoxia and defective apoptosis drive genomic instability and tumorigenesis,” Genes Dev., vol. 18, no. 17, pp. 2095-2107, Sep. 2004, doi: 10.1101/gad.1204904.
[13] H. A. Alagizy, M. R. Soltan, S. S. Soliman, N. N. Hegazy, and S. F. Gohar, “Anxiety, depression and perceived stress among breast cancer
patients: single institute experience,” Middle East Curr. Psychiatry, vol. 27, no. 1, 2020, doi: 10.1186/s43045-020-00036-x.
[14] M. R. Hassan, S. A. Shah, H. F. Ghazi, and N. M. M. Mujar, “Anxiety and depression among breast cancer patients in an urban setting in Malaysia,” Asian Pac J Cancer Prev, vol. 16, no. 22, pp. 4031-4035, 2015.
[15] M. A. Vahdaninia and S. Omidvari, “What do predict anxiety and depression in breast cancer patients? A follow-up study,” Soc Psychiatry
Psychiatr Epidemiol, vol. 45, no. 3, pp. 55-61, 2010, doi: 10.1007/s00127-009-0068-7.
[16] N. C. Zainal, N. R. Nik-Jaafar, A. Baharudin, and Z. A. Sabki, “Prevalence of depression in breast cancer survivors: a systematic review of observational studies,” Asian Pac J Cancer Prev, vol. 14, pp. 2649-2656, 2013.
[17] B. S. Dastan, “Depression and anxiety levels in early stage Turkish breast cancer patients and related factors,” Asian Pacific J Cancer Prev, vol. 12, pp. 137-141, 2011.
[18] D. Wellisch and A. Hoffman, “Depression and anxiety symptoms in women at high risk for breast cancer: pilot study of a group intervention,” Am J Psychiatry, vol. 156, pp. 1644-1645, 1999.
[19] N. Nikbakhsh, S. Moudi, S. Abbasian, and S. Khafri, “Prevalence of depression and anxiety among cancer patients,” Casp. J. Intern. Med.,
vol. 5, no. 3, pp. 167-170, 2014.
[20] A. P. Macmillan, “Depression and anxiety in patients with cancer consultant liaison psychiatrist, senior clinical lecturer in psychiatry Sources and selection criteria How common are depression and anxiety in patients with cancer?,” BMJ, pp. 1-11, 2018, doi: 10.1136/bmj.k1415.
[21] Ng, C. G., Mohamed, S., Kaur, K., Sulaiman, A. H., Zainal, N. Z., & Taib, N. A. (2017). Perceived distress and its association with depression and anxiety in breast cancer patients. PLoS ONE, 12(3), 1-10. https://doi.org/10.1371/journal.pone.0172975.
[22] N. Aass, S. D. Fosså, A. A. Dahl, and T. J. Moe, “Prevalence of anxiety and depression in cancer patients seen at the Norwegian radium hospital,” Eur. J. Cancer, vol. 33, no. 10, pp. 1597-1604, 1997, doi: 10.1016/S0959-8049(97)00054-3.