DRUG INTERACTIONS IN OUTPATIENT TREATMENT AT THOT NOT GENERAL HOSPITAL

Abstract

Objective: Analyzing drug interactions in outpatient treatment at Thot Not District General Hospital in 2020.
Subjects and methods: cross-sectional study on 400 prescriptions for insured patients with outpatient medical records at Thot Not general hospital from January 1st, 2020 to June 30th, 2020.
Results: Five pairs of clinically significant drug interactions were recorded with the databases used in the study. The rate of prescription of drug interactions with clinical significance was 11%. The number of prescriptions with a drug interaction accounted for the highest proportion (10.8%) and only one prescription with two drug interactions detected (0.2%). The pair of drug interactions that
appeared with the most frequency were clopidogrel and proton pump inhibitors (34.1%), followed by interactions between aspirin and NSAIDs (25%), interactions between codeine and clopheniramin
(20.4%). There was no relationship between the patient’s age and the ability of drug interactions (p> 0.05) but there was an association between the sex and the amount of drugs used in the prescription
and the ability of drug interactions was statistically significant (p <0.05).
Conclusion: The rate of prescription drug interactions with clinical significance was 11%. The pair of drug interactions that appeared with the most frequency were clopidogrel and proton pump inhibitors
(34.1%). There was an association between the sex and the amount of drugs used in the prescription and the ability of drug interactions was statistically significant (p <0.05)