1. RELATIONSHIP BETWEEN QUALITY OF LIFE AND CLINICAL FEATURES OF CIRCULAR PATIENTS RECEIVING INPATIENT TREATMENT AT BACH MAI HOSPITAL
Main Article Content
Abstract
Objective: Analysis of the relationship between quality of life and some paraclinical clinical characteristics of cirrhosis patients hospitalized at Bach Mai hospital, 2023 - 2024.
Research subjects and methods: Cross-sectional descriptive study, conducted at the Center for Tropical Diseases and the Hepatobiliary Digestive Center of Bach Mai Hospital from March 2023 to March 2024. The study included 216 people with cirrhosis who met the selection criteria. The study used the Chronic Liver Disease Questionarie (CLDQ) scale to measure QoL.
Results: The majority of patients had average quality of life (QoL) and good quality of life, 75% and 25%, respectively. No one has low QoL. Clinical factors related to reduced quality of life include: ascites (OR=3.04, p<0.001), jaundice, yellow eyes (OR= 2.52 p=0.003)), nausea, vomiting (OR = 2.16, p = 0.015), gastrointestinal bleeding (OR = 3.57, p < 0.001. Paraclinical factors related to decreased QOL are decreased red blood cells (OR = 1.75 , p=0.13); decreased albumin (OR =3.24, p=0.003).
Conclusion: Cirrhosis clearly affects the quality of life of people with the disease. Monitoring and early detection of clinical and paraclinical signs such as ascites, jaundice, yellow eyes, bloating and reduced red blood cell count, plasma albumin, and blood clotting time contribute to improving QoL and effectiveness. treatment for patients with cirrhosis.
Article Details
Keywords
Quality of life, cirrhosis, Chronic Liver Disease Questionnaire (CLDQ).
References
of life in patients with nonalcoholic fatty liver disease;
Aliment Pharmacol Ther. 2007, 26(6): 815–820. doi: 10,1111/j,1365-
2036,2007,03426.x.
Bảng 4.1. So sánh điểm chất lượng cuộc sống các
khía cạnh với các nghiên cứu khác Các khía cạnh về
CLCS Điểm trung bình trong các nghiên cứu
Kar.H Dusan D Montserrat Chúng tôi
Triệu chứng ổ bụng 4.89 ± 1.44 4.75 ± 1.63 5.13 ± 1.11 4,49 ± 0,76
Sự mệt mỏi 4.24 ± 1.48 4.2 ± 1.60 5.79 ± 1.39 4,63 ± 0,69
Triệu trứng toàn thân 5.04 ± 1.27 5.27 ± 1.60 4.87 ± 1.46 4,88 ± 0,62
Hoạt động sống 4.72 ± 1.62 4.47 ± 1.33 5.31 ± 1.24 4,70 ± 0,72
Cảm xúc, tình cảm 4.83 ± 1.28 4.61 ± 1.61 5.18 ± 1.57 4,9 ± 0,57
Lo lắng 4.11 ± 1.56 4.24 ± 1.61 5.10 ± 1.26 5,38 ± 0,48
Tổng điểm CLCS 4.62 ± 1.20 4.62 ± 1.11 5.18 ± 1.11 4,87 ± 0,54N.
[2] Abhasnee S, Chatchawan S, Ronnachai K et
al.,Factors influencing health-related quality of
life in chronic liver disease" World Journal
of Gastroenterology, 2006, 12(48): 7786-7791.
[3] Dusan DP, Nada VK, Darija KT et al.,;Valiadation
of the chronic liver disease questionaire in Serbian
patients; World Jounrnal of Gastroenterology,
2013
[4] K Janani, Mayank J, Joy V et al.,Health-related
quality of life in liver cirrhosis patients using
SF-36 and CLDQ questionnaires; Clinical and
Experimental Hepatology. 2018, 4(4): 232–239.
[5] Maryam E, Marzieh P, Quality of life in Patients
With Liver Cirrhosis: A Systematic Review; Hosp
Pract Res, 2019, 4(4) 111 - 116.
[6] Silvia N, Ilaria P, Chiara P et al.,Depression,
anxiety and alexithymia symptoms are major
determinants of health related quality of life
(HRQoL) in cirrhotic patients; Metab Brain Dis,
2013
[7] Irene R, Deep D, Pallavi B et al., Quality of life
assessment of patients with chronic liver disease
in eastern India using a Bengali translation
chronic liver disease questionnaire",
Indian J Gastroenterol, 2010. 29: 187-195.
[8] Feng G, Ru G, Guang L et al., Health-Related
Quality of Life in Chinese Patients with Chronic
Liver Disease", Gastroenterology
Research and Practice. Volume 2012, Article ID
516140, 7 pages.
[9] Silpakit C, Sobhonslidsuk A, Kongsakon R et al.,
Chronic liver disease questionnaire: translation
and validation in Thais; World Jgastroenterol, Jul
1; 2004, 10(13):1954-7.
[10] Adib-Hajbagheri M, Zandi M, Memarian R et al.,
Effects of aself-care program on quality of life of
cirrhotic patients referring to Tehran Hepatitis
Center, Health Qual Life Outcomes, 2005.
[11] Kok B, Whitlock R, Ferguson T et al., HealthRelated
Quality of life; A Rapid Predictor
of Hospitalization in Patiens With Cirrhosis.
Am J Gastroenterol. 2020;115(4):575-583.
doi:10.14309/ajg.0000000000000545