Nguyen Anh Tho1, Ngo Toan Anh2, Nguyen Xuan Hoi2, Nguyen Viet Tien3
1 Hatinh Provincial Medical college
2 National Hospital of Obstetrics and Gynecology
3 Hanoi Medical University

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Objectives: To assess the outcome of Flare-up versus Antagonist protocol and to determine factors related to poor responders.
Methodology: this is a random control trial among 834 patients who were predicted to ovarian poor response from 2014 to 2018.
Results: The rate of biochemical pregnancy was 4.5% with Flare-up versus 8,1% with Antagonist (p<0.05). The rate of fertilization, implantation and clinical pregnancy were not significant different
between the 2 protocols. Age and number of AFC were significant factors to predict poor ovarian response. However, with Flare-up, there were 2 more factors could be used for the purpose which
was basal FSH and E2 day 7.
Conclusion: The outcome of treatment between Flare-up and Antagonist among predicted poor ovarian response was comparable. Age and AFC were valuable factors in prediction of poor ovarian

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