8. LIVER CANCER IN VIETNAM AND ASIA FROM 2013 TO 2023: EPIDEMIOLOGICAL TRENDS AND CONTRIBUTING RISK FACTORS – A SCOPING REVIEW
Nội dung chính của bài viết
Tóm tắt
Objectives: This scoping review explored liver cancer incidence, mortality trends, and risk factors in Vietnam and Asia from 2013 to 2023, using the PCC framework (Population, Concept, Context).
Methods: Following PRISMA-ScR guidelines, a literature search was conducted using PubMed, Web of Science, and Vietnamese sources. Eligible studies were selected and synthesized thematically to provide a comprehensive view.
Results: Thirty-three studies were included. Vietnam and several Asian countries reported some of the highest liver cancer rates globally, with age-standardized incidence rates reaching 20.2 per 100,000 in Vietnam, 25.7 in China, and 31.0 in Mongolia, according to GLOBOCAN 2022 data. Major risk factors include HBV/HCV infections, aflatoxin exposure, alcohol, metabolic disorders, environmental pollution, and poor healthcare access.
Conclusions: The burden of liver cancer remains high in Vietnam and Asia. Comprehensive public health interventions addressing both infectious and lifestyle-related factors, along with improvements in healthcare infrastructure, are urgently needed to address the growing health challenges.
Chi tiết bài viết
Từ khóa
liver cancer, Vietnam, Asia, incidence, mortality, risk factors, HBV, aflatoxins
Tài liệu tham khảo
[2] WHO. Global Hepatitis Report. 2017.
[3] IARC. GLOBOCAN 2022 database.
[4] Nguyen M. Cancer statistics in Vietnam. J Pract Med. 2023;111(3):12–20.
[5] Le QN, et al. HBsAg prevalence among hepatocellular carcinoma (HCC) patients in Vietnam. J Oncol Res. 2019;12(4):44–50.
[6] Le TV, et al. Aflatoxin exposure in rural Vietnamese children. Food Chem Toxicol. 2020;145:111678.
[7] Loomba R, et al. Obesity, diabetes, and HCC. Hepatology. 2013;58(1):291–300.
[8] Yu MW, et al. Family history and HBV-related HCC. J Natl Cancer Inst. 2017;109(6):djw253.
[9] Nguyen DS, et al. Socioeconomic disparity in liver cancer. Vietnam Med J. 2022;88(1):55–63.
[10] Ma X, et al. Liver cancer trends in Hong Kong: 1991–2020. Asian Pac J Cancer Prev. 2023;24(1):103–109.