4. CÁC KỸ THUẬT MỚI TRONG CHẨN ĐOÁN NHIỄM TRÙNG NẤM: TỔNG QUAN
Nội dung chính của bài viết
Tóm tắt
Hiện nay có rất nhiều phương pháp dùng để chẩn đoán nấm đã ra đời và được áp dụng tại các cơ sở y tế, tuy nhiên mỗi phương pháp sẽ có những ưu - nhược điểm khác nhau như độ nhạy, độ chính xác, thời gian,... Để cải thiện độ chính xác và tốc độ chẩn đoán nhanh nhiễm trùng nấm, một số phương pháp mới đã ra đời dựa trên sự kết hợp những phương pháp cũ sẵn có. Hầu hết các phương pháp cải tiến này đều độc lập với việc phân lập mầm bệnh, điều đó có nghĩa là chẩn đoán chuyển từ được coi là đã được chứng minh sang có khả năng xảy ra. Mặc dù có lợi thế là không phụ thuộc vào nuôi cấy, nhưng phần lớn các phương pháp đều thiếu sự chuẩn hóa. Bài tổng quan này nhằm mục đích xem xét phương pháp chẩn đoán nhiễm trùng nấm toàn thân, từ phân loại chẩn đoán, thông qua các phương pháp được coi là "tiêu chuẩn vàng", đến các phương pháp phân tử hiện đang được sử dụng và cuối cùng đề cập đến một số phương pháp tiếp cận mang tính tương lai hơn.
Chi tiết bài viết
Từ khóa
Candida, nấm, kỹ thuật chẩn đoán
Tài liệu tham khảo
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[24] L. Potocki, J. Depciuch, E. Kuna, M. Worek, A. Lewinska, and M. Wnuk, "FTIR and Raman spectroscopy-based biochemical profiling reflects genomic diversity of clinical Candida isolates that may be useful for diagnosis and targeted therapy of candidiasis," International journal of molecular sciences, vol. 20, no. 4, p. 988, 2019.
[25] V. Erukhimovitch, V. Pavlov, M. Talyshinsky, Y. Souprun, and M. Huleihel, "FTIR microscopy as a method for identification of bacterial and fungal infections," Journal of pharmaceutical and biomedical analysis, vol. 37, no. 5, pp. 1105-1108, 2005.
[26] S. Hu et al., "Rapid detection method for pathogenic Candida captured by magnetic nanoparticles and identified using SERS via AgNPs+," International Journal of Nanomedicine, pp. 941-950, 2021.
[27] T. Sojinrin et al., "Plasmonic gold nanoparticles for detection of fungi and human cutaneous fungal infections," Analytical and bioanalytical chemistry, vol. 409, pp. 4647-4658, 2017.
[28] N. Peker, N. Couto, B. Sinha, and J. W. Rossen, "Diagnosis of bloodstream infections from positive blood cultures and directly from blood samples: recent developments in molecular approaches," Clinical Microbiology and Infection, vol. 24, no. 9, pp. 944-955, 2018.
[29] E. Mylonakis et al., "T2 magnetic resonance assay for the rapid diagnosis of candidemia in whole blood: a clinical trial," Clinical Infectious Diseases, vol. 60, no. 6, pp. 892-899, 2015.
[30] L. Pla et al., "Oligonucleotide-capped nanoporous anodic alumina biosensor as diagnostic tool for rapid and accurate detection of Candida auris in clinical samples," Emerging microbes & infections, vol. 10, no. 1, pp. 407-415, 2021.
[31] M. G. Gerritsen et al., "Profiling of volatile organic compounds produced by clinical Aspergillus isolates using gas chromatography–mass spectrometry," Medical mycology, vol. 56, no. 2, pp. 253-256, 2018.
[2] F. Bongomin, S. Gago, R. O. Oladele, and D. W. Denning, "Global and multi-national prevalence of fungal diseases—estimate precision," Journal of fungi, vol. 3, no. 4, p. 57, 2017.
[3] G. Janbon, J. Quintin, F. Lanternier, and C. d’Enfert, "Studying fungal pathogens of humans and fungal infections: Fungal diversity and diversity of approaches," Microbes and Infection, vol. 21, no. 5-6, pp. 237-245, 2019.
[4] A. H. Damasceno-Escoura et al., "Histoplasmosis in HIV-infected patients: epidemiological, clinical and necropsy data from a Brazilian teaching hospital," Mycopathologia, vol. 185, pp. 339-346, 2020.
[5] S. Sharma, M. Grover, S. Bhargava, S. Samdani, and T. Kataria, "Post coronavirus disease mucormycosis: a deadly addition to the pandemic spectrum," The Journal of Laryngology & Otology, vol. 135, no. 5, pp. 442-447, 2021.
[6] S. Gokulshankar and B. K. Mohanty, "COVID-19 and black fungus," Asian J Med Health Sci, vol. 4, no. 1, p. 138, 2021.
[7] A. Hagen, "COVID-19-associated mucormycosis: triple threat of the pandemic," 2022.
[8] A. Mendonca, H. Santos, R. Franco-Duarte, and P. Sampaio, "Fungal infections diagnosis–past, present and future," Research in Microbiology, vol. 173, no. 3, p. 103915, 2022.
[9] A. S. Chouhan, B. Parihar, and B. Rathod, "Overuse of Steroid Drugs Methylprednisolone and Dexamethasone (Oral) Causes a Diabetic Patient to Become Infected With the Black Fungus of the Corona Virus," 2021.
[10] C. Prestel, "Candida auris outbreak in a COVID-19 specialty care unit—Florida, July–August 2020," MMWR. Morbidity and mortality weekly report, vol. 70, 2021.
[11] J. V. Mulet Bayona et al., "Impact of the SARS-CoV-2 pandemic in candidaemia, invasive aspergillosis and antifungal consumption in a tertiary hospital," Journal of Fungi, vol. 7, no. 6, p. 440, 2021.
[12] R. Franco-Duarte et al., "Advances in chemical and biological methods to identify microorganisms—from past to present," Microorganisms, vol. 7, no. 5, p. 130, 2019.
[13] J. R. Bao, R. N. Master, R. S. Jones, R. B. Clark, E. C. Moore, and K. L. Shier, "Recovery and its dynamics of filamentous fungi from clinical specimen cultures: an extensive study," Microbiology Spectrum, vol. 9, no. 1, pp. 10-1128, 2021.
[14] A. M. Borman, M. Fraser, and E. M. Johnson, "CHROMagarTM Candida Plus: A novel chromogenic agar that permits the rapid identification of Candida auris," Medical mycology, vol. 59, no. 3, pp. 253-258, 2021.
[15] Y.-S. Huang et al., "High rates of misidentification of uncommon Candida species causing bloodstream infections using conventional phenotypic methods," Journal of the Formosan Medical Association, vol. 120, no. 5, pp. 1179-1187, 2021.
[16] C. Lass-Flörl, E. Samardzic, and M. Knoll, "Serology anno 2021—fungal infections: from invasive to chronic," Clinical Microbiology and Infection, vol. 27, no. 9, pp. 1230-1241, 2021.
[17] B. D. Alexander et al., "Guidance on imaging for invasive pulmonary aspergillosis and mucormycosis: from the imaging working group for the revision and update of the consensus definitions of fungal disease from the EORTC/MSGERC," Clinical Infectious Diseases, vol. 72, no. Supplement_2, pp. S79-S88, 2021.
[18] I. Camp, G. Manhart, C. Schabereiter-Gurtner, K. Spettel, B. Selitsch, and B. Willinger, "Clinical evaluation of an in-house panfungal real-time PCR assay for the detection of fungal pathogens," Infection, vol. 48, pp. 345-355, 2020.
[19] P. L. White et al., "Nucleic acid tools for invasive fungal disease diagnosis," Current Fungal Infection Reports, vol. 14, pp. 76-88, 2020.
[20] J. Carvalho-Pereira et al., "Multiplex PCR based strategy for detection of fungal pathogen DNA in patients with suspected invasive fungal infections," Journal of Fungi, vol. 6, no. 4, p. 308, 2020.
[21] L. M. E. Vanhee, E. D’Haese, I. Cools, H. J. Nelis, and T. Coenye, "Detection and quantification of bacteria and fungi using solid-phase cytometry," pp. 25-41: Springer.
[22] L. M. E. Vanhee, H. J. Nelis, and T. Coenye, "Rapid detection and quantification of Aspergillus fumigatus in environmental air samples using solid-phase cytometry," Environmental science & technology, vol. 43, no. 9, pp. 3233-3239, 2009.
[23] L. M. E. Vanhee, W. Meersseman, K. Lagrou, J. Maertens, H. J. Nelis, and T. Coenye, "Rapid and direct quantification of viable Candida species in whole blood by use of immunomagnetic separation and solid-phase cytometry," Journal of clinical microbiology, vol. 48, no. 4, pp. 1126-1131, 2010.
[24] L. Potocki, J. Depciuch, E. Kuna, M. Worek, A. Lewinska, and M. Wnuk, "FTIR and Raman spectroscopy-based biochemical profiling reflects genomic diversity of clinical Candida isolates that may be useful for diagnosis and targeted therapy of candidiasis," International journal of molecular sciences, vol. 20, no. 4, p. 988, 2019.
[25] V. Erukhimovitch, V. Pavlov, M. Talyshinsky, Y. Souprun, and M. Huleihel, "FTIR microscopy as a method for identification of bacterial and fungal infections," Journal of pharmaceutical and biomedical analysis, vol. 37, no. 5, pp. 1105-1108, 2005.
[26] S. Hu et al., "Rapid detection method for pathogenic Candida captured by magnetic nanoparticles and identified using SERS via AgNPs+," International Journal of Nanomedicine, pp. 941-950, 2021.
[27] T. Sojinrin et al., "Plasmonic gold nanoparticles for detection of fungi and human cutaneous fungal infections," Analytical and bioanalytical chemistry, vol. 409, pp. 4647-4658, 2017.
[28] N. Peker, N. Couto, B. Sinha, and J. W. Rossen, "Diagnosis of bloodstream infections from positive blood cultures and directly from blood samples: recent developments in molecular approaches," Clinical Microbiology and Infection, vol. 24, no. 9, pp. 944-955, 2018.
[29] E. Mylonakis et al., "T2 magnetic resonance assay for the rapid diagnosis of candidemia in whole blood: a clinical trial," Clinical Infectious Diseases, vol. 60, no. 6, pp. 892-899, 2015.
[30] L. Pla et al., "Oligonucleotide-capped nanoporous anodic alumina biosensor as diagnostic tool for rapid and accurate detection of Candida auris in clinical samples," Emerging microbes & infections, vol. 10, no. 1, pp. 407-415, 2021.
[31] M. G. Gerritsen et al., "Profiling of volatile organic compounds produced by clinical Aspergillus isolates using gas chromatography–mass spectrometry," Medical mycology, vol. 56, no. 2, pp. 253-256, 2018.