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Đã xuất bản: 2024-12-12
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DOI: https://doi.org/10.52163/yhc.v65i13.1790
Số xuất bản
Tập 65 Số Tiếng Anh
Chuyên mục
Bài báo khoa học
Cách trích dẫn
Hue, P. T. K., Thao, D. T., Loc, T. V. ., Duong, N. T., Quynh Ngan, T. T., Ngoc, N. L. B., Dung, D. H., Minh, L. N., & Vien, L. T. (2024). 9. EFFECTS OF GLYCEMIC REGULATION AND ACETYLCHOLINESTERASE INHIBITION OF SCORPION TURMERIC (CURCUMA RANGJUED) IN CENTRAL HIGHLANDS, VIETNAM. Tạp Chí Y học Cộng đồng, 65(Tiếng Anh). https://doi.org/10.52163/yhc.v65i13.1790

9. EFFECTS OF GLYCEMIC REGULATION AND ACETYLCHOLINESTERASE INHIBITION OF SCORPION TURMERIC (CURCUMA RANGJUED) IN CENTRAL HIGHLANDS, VIETNAM

Phung Thi Kim Hue1,2, Do Thi Thao1,3, Tran Van Loc1,4, Nguyen Thi Duong5, Tran Thi Quynh Ngan2, Nguyen Le Bao Ngoc2, Do Hoang Dung2, Le Nhat Minh6, Le Tri Vien1
1 Institute of Health Research and Educational Development in Central Highlands
2 Hung Vuong High School for the Gifted
3 Institute of Biotechnology, Vietnam Academy of Science and Technology
4 Institute of Chemistry, Vietnam Academy of Science and Technology
5 Thao Nguyen Duong Family Heirloom Traditional Medicine Clinic
6 Foreign Trade University

Nội dung chính của bài viết

Tóm tắt

Scorpion turmeric has been traditionally grown in the Central Highlands provinces of Vietnam. Prepared medicinal products from this species (Curcuma rangjued) are currently used in folk medicine to treat various illnesses including bronchitis, asthma, gastritis, and typically used as an antiseptic. Despite its popular use, scientific studies into its pharmacological properties remain limited. Chemical analysis has revealed the presence of many valuable bioactive ingredients such as D-limonene, β-pinene, and caryophyllene, which exhibit high pharmaceutical potential due to antioxidant and anti-inflammatory activities (Athanasaki et al., 2022). Therefore, exploiting the medicinal resource from the scorpion turmeric plant will bring various benefits to community health care.


Objectives: This study aimed to evaluate the glycemic regulation and acetylcholinesterase (AChE) inhibitory effects of the scorpion turmeric’s rhizome extracts.


Methods: Blood glucose levels were measured using the method described by Sivalingam (2013), while AChE inhibitory activity was determined according to the method of Ellman et al. (1961).


Results: The results have shown that scorpion turmeric’s rhizome extracts which contain D-limonene, β-pinene and caryophyllene, demonstrated significant anti-inflammatory properties. Moreover, they exhibited both in vitro and in vivo glycemic regulatory effects and inhibited AChE activity in vitro.


Conclusion: The findings of this study suggest that C. rangjued possess considerable therapeutic potential for the management of diabetes and Alzheimer's disease. Therefore, the scorpion turmeric plant should be given more attention and developed to preserve this valuable medicinal resource.

Chi tiết bài viết

Từ khóa

Diabetes, Alzheimer, AchE, Curcuma rangjued, Scorpion turmeric

Tài liệu tham khảo

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