6. TAXONOMIC IDENTIFICATION OF AN ADDITIONAL SPECIES, CURCUMA RANGJUED, IN THE CENTRAL HIGHLANDS OF VIETNAM AND EVALUATION OF ITS INHIBITORY ACTIVITIES AGAINST CANCER CELL LINES

Phung Thi Kim Hue1,2, Nguyen Quoc Binh3, Do Thi Thao1,4, Nguyen Phuong Hanh5, Nguyen Thi Duong6, Tran Thi Quynh Ngan2, Nguyen Le Bao Ngoc2, Do Hoang Dung2, Tran Van Loc1,7, Le Nhat Minh8, Le Tri Vien1
1 Institute of Health Research and Educational Development in Central Highlands
2 Hung Vuong High School for the Gifted
3 Vietnam National Museum of Nature, Vietnam Academy of Science and Technology
4 Institute of Biotechnology, Vietnam Academy of Science and Technology
5 Institute of Ecology and Biological Resource, Vietnam Academy of Science and Technology
6 Thao Nguyen Duong Family Heirloom Traditional Medicine Clinic
7 Institute of Chemistry, Vietnam Academy of Science and Technology
8 Foreign Trade University

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Tóm tắt

Curcuma L. is a large genus in the Zingiberaceae, many species have been used as spices, medicines, dyes, some plants are grown as ornamentals. Curcuma rangjued has been grown for many years in the Central Highlands provinces of Vietnam. Traditional medicine products from Curcuma rangjued are used to treat common diseases, such as respiratory tract infections, bronchitis, asthma, stomachache, skin inflammation. However, the plant is only locally known as scorpion turmeric, based on the shape of the rhizome of this plant, without a scientific name. It is unlike any turmeric species found in China, Laos, Cambodia and Vietnam with the following characteristics: inflorescences growing between leaf sheaths; abaxially green, usually with red patches on along side of midvein, fertile bract pale green; coma bract pale red, white towards basal. Notably, the rhizome has an intensely bitter taste.


In this study, we identified and taxonomically described a new species of turmeric, Curcuma rangjued, contributing to the taxonomic diversity of Vietnam. Furthermore, pharmacological investigations revealed that the rhizome extract of C. rangjued exhibited significant inhibitory effects on the proliferation of four human cancer cell lines: A549 (lung carcinoma), MCF-7 (breast carcinoma), HT-29 (colorectal carcinoma), and SNU-1 (gastric carcinoma).

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Tài liệu tham khảo

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