CASES REPORT: INFECTIOUS FUNGAL SCLERITIS FOLLOWING PTERYGIUM SURGERY

La Van Long1, Le Xuan Cung2, Duong Mai Nga2
1 Đại học Y Hà Nội
2 Vietnam National Institute of Ophthalmology

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Abstract

Scleritis is a rare inflammatory ocular disease characterized by intense inflammation and severe ocular pain. The condition is highly destructive to ocular tissues; without timely diagnosis and intervention, it can lead to devastating complications, including permanent vision loss. We report two clinical cases of necrotizing fungal scleritis following pterygium surgery, with diagnoses confirmed through microbiological testing. Both patients presented with severe pain occurring between ten days and fourteen days post-operatively, showing no response to initial treatment with antibiotics and corticosteroids. The scleritis lesions originated at the surgical site and expanded circumferentially along the anterior sclera. Both patients were successfully managed using a multimodal treatment approach, comprising surgical debridement of necrotic scleral and conjunctival tissues (leaving the sclera bare) combined with intensive topical and systemic antifungal therapy. 

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References

1) Jain, V., Garg, P., & Sharma, A. (2010). Scleritis: Differentiating infectious from noninfectious entities. Cornea, 29(1), 125-128. doi: 10.1097/ICO.0b013e3181a4dcd0
2) Pavesio, C. (Ed.). (2017). Scleritis. Cham: Springer International Publishing.
3) Watson, P. G., & Hayreh, S. S. (1976). Scleritis and episcleritis. British Journal of Ophthalmology, 60(3), 163-191. doi: 10.1136/bjo.60.3.163
4) Ahn, S. J., Oh, J. Y., Kim, M. K., & Lee, J. H. (2010). Clinical features, predisposing factors, and treatment outcomes of scleritis in the Korean population. Korean Journal of Ophthalmology, 24(6), 331-337. doi: 10.3341/kjo.2010.24.6.331
5) O'Donoghue, E., Lightman, S., Tuft, S., & Watson, P. G. (1992). Surgically induced necrotising sclerokeratitis (SINS)—precipitating factors and response to treatment. The British Journal of Ophthalmology, 76(1), 17–21. doi: 10.1136/bjo.76.1.17
6) Sharma S, Sheth JU, Murthy SI. Infectious scleritis: a review of etiologies, clinical features, and management strategies. Front Ophthalmol (Lausanne). 2025 Feb 7;5:1493831. doi: 10.3389/fopht.2025.1493831. PMID: 39990248; PMCID: PMC11842368.
7) Murthy SI, Sabhapandit S, Balamurugan S, Subramaniam P, Sainz-de-la-Maza M, Agarwal M, Parvesio C. Scleritis: Differentiating infectious from non-infectious entities. Indian J Ophthalmol. 2020 Sep;68(9):1818-1828. doi: 10.4103/ijo.IJO_2032_20. PMID: 32823398; PMCID: PMC7690484.
8) Ruiz-Lozano RE, Garza-Garza LA, Davila-Cavazos O, Foster CS, Rodriguez-Garcia A. The clinical and pathogenic spectrum of surgically-induced scleral necrosis: A review. Surv Ophthalmol. 2021 Jul-Aug;66(4):594-611. doi: 10.1016/j.survophthal.2020.12.008. Epub 2021 Jan 8. PMID: 33422510.