RISK FACTORS ASSOCIATED WITH POSTPARTUM HEMORRHAGE FOLLOWING VAGINAL DELIVERY AT HAI PHONG OBSTETRICS AND GYNECOLOGY HOSPITAL

Nguyen Thi Hoang Trang1, Pham Thanh Nhan1
1 Department of Obstetrics and Gynecology, Hai Phong University of Medicine and Pharmacy

Main Article Content

Abstract

Objectives: To identify independent factors associated with postpartum hemorrhage following vaginal delivery at Hai Phong Obstetrics and Gynecology Hospital, 2020-2026.


Methods: A 1:2 matched case-control study using retrospective medical record review, comprising 61 postpartum hemorrhage cases and 122 controls matched by maternal age, residence, parity, and gestational age. Conditional logistic regression was applied; results expressed as adjusted odds ratios (aOR) with 95% confidence intervals.


Results: 4 independent factors were significantly associated with postpartum hemorrhage: macrosomia > 4000g (aOR = 15.42; 95% CI: 3.21-74.1; p = 0.001), polyhydramnios (aOR = 12.65; 95% CI: 1.48-108.2; p = 0.020), history of postpartum hemorrhage (aOR = 10.12; 95% CI: 1.65-62.0; p = 0.012), and anemia hemoglobin < 110 g/L (aOR = 3.14; 95% CI: 1.45-6.82; p = 0.004).


Conclusion: 4 independent risk factors were identified with direct applicability for developing postpartum hemorrhage risk screening tools and active prevention protocols.

Article Details

References

[1] WHO, UNICEF, UNFPA, World Bank Group, and UNDESA/Population Division. Trends in maternal mortality 2000 to 2020: estimates by WHO, UNICEF, UNFPA, World Bank Group and UNDESA/Population Division, 2023. https://iris.who.int/handle/10665/366225.
[2] Evensen A, Anderson J.M, Fontaine P. Postpartum hemorrhage: prevention and treatment. American Family Physician, 2017, 95 (7): 442-449.
[3] Võ Thị Mỹ Dung, Trương Quang Vinh. Nghiên cứu các nguyên nhân băng huyết sau sinh và kết quả điều trị tại Bệnh viện Đa khoa tỉnh Ninh Thuận. Tạp chí Phụ Sản, 2023, 20 (4): 50-55. doi: 10.46755/vjog.2022.4.1364.
[4] Nguyễn Gia Định. Nghiên cứu các yếu tố liên quan đến băng huyết sau sinh do đờ tử cung và hiệu quả điều trị bằng chèn bóng lòng tử cung. Luận án tiến sĩ y học, Trường Đại học Y Dược Huế, Đại học Huế, 2020.
[5] Gestational hypertension and preeclampsia: ACOG Practice Bulletin, number 222. Obstetrics & Gynecology, 2020, 135 (6): e237-e260. doi: 10.1097/AOG.0000000000003891.
[6] Escobar M.F, Nassar A.H, Theron G et al. FIGO recommendations on the management of postpartum hemorrhage 2022. Int J Gynaecol Obstet, 2022, 157 (Suppl 1): 3-50.
[7] Wetta L.A, Szychowski J.M et al. Risk factors for uterine atony/postpartum hemorrhage requiring treatment after vaginal delivery. Am J Obstet Gynecol, 2013, 209 (1): 51.e1-51.e6. doi: 10.1016/j.ajog.2013.03.011
[8] Phạm Thanh Hải và cộng sự. Yếu tố nguy cơ băng huyết sau sinh. Đề tài nghiên cứu khoa học cấp cơ sở, Bệnh viện Từ Dũ, 2008.
[9] Al-Zirqi I, Vangen S, Forsen L, Stray-Pedersen B. Prevalence and risk factors of severe obstetric haemorrhage. BJOG: An International Journal of Obstetrics & Gynaecology, 2008, 115 (10): 1265-1272. doi: 10.1111/j.1471-0528.2008.01859.x.
[10] Oberg A.S, Hernandez-Diaz S, Palmsten K et al. Patterns of recurrence of postpartum hemorrhage in a large population-based cohort. Am J Obstet Gynecol, 2014, 210 (3): 229.e1-229.e8. doi: 10.1016/j.ajog.2013.10.877.