MANAGEMENT OF SEVERE PERISTOMAL INFECTION FOLLOWING LONG-TERM PERCUTANEOUS ENDOSCOPIC GASTROSTOMY: A CASE REPORT

Le Thi Hang1, Nguyen Huu Quan1, Le Quang Tri1, Nguyen Thi Tham2, Nguyen Thu Huong2, Nguyen Thi Phuong2, Nguyen Thi Nhi2, Nguyen Hoang Nam2, Tran Thi Thuy Huong3
1 Bach Mai Hospital
2 Hanoi Medical University Hospital
3 Dong Da General Hospital

Main Article Content

Abstract

Background: Percutaneous endoscopic gastrostomy (PEG) is widely used for long-term enteral feeding. Peristomal infection and gastrointestinal leakage are recognised complications, whereas deep abdominal wall extension with persistent leakage is uncommon.


Case presentation: A 72-year-old man with type 2 diabetes mellitus, sequelae after cardiac arrest, tracheostomy, and PEG feeding for more than 3 years developed fever, impaired consciousness, profuse peristomal gastric leakage, and extensive anterior abdominal wall inflammation 3 days after routine PEG tube replacement. On admission, findings were consistent with severe infection, hyperosmolar hyperglycaemic state, and acute kidney injury.


Intervention and outcomes: Management included intensive resuscitation, broad-spectrum antibiotics, PEG tube removal, gastric decompression, jejunal tube placement for enteral feeding, and negative pressure wound therapy. Leakage progressively decreased, granulation tissue developed satisfactorily, and complete wound healing was achieved after 58 days.


Conclusion: In severe peristomal PEG infection with persistent gastrointestinal leakage, a combined approach incorporating infection control, source control, maintenance of enteral nutrition, and negative pressure wound therapy may result in favourable outcomes. Early recognition and close local monitoring remain essential.

Article Details

References

[1] Fugazza A, Capogreco A, Cappello A et al. Percutaneous endoscopic gastrostomy and jejunostomy: indications and techniques. World J Gastrointest Endosc, 2022, 14 (5): 250-266. doi: 10.4253/wjge.v14.i5.250
[2] Tae C.H, Lee J.Y, Joo M.K et al. Clinical practice guidelines for percutaneous endoscopic gastrostomy. Clin Endosc, 2023, 56 (4): 391-408. doi: 10.5946/ce.2023.062
[3] Choi I.H, Cho Y.K. Percutaneous endoscopic gastrostomy: procedure, complications and management. Brain Neurorehabil, 2022, 15 (1): e2. doi: 10.12786/bn.2022.15.e2
[4] Boeykens K, Duysburgh I, Verlinden W. Prevention and management of minor complications in percutaneous endoscopic gastrostomy. BMJ Open Gastroenterol, 2022, 9 (1). doi: 10.1136/bmjgast-2022-000975
[5] Rıdvan S, Güldan K, Rana B. Percutaneous endoscopic gastrostomy complications and management. Discover Medicine, 2026, 3 (1): 1. doi: 10.1007/s44337-025-00525-0
[6] Pepe G, Chiarello M.M, Bianchi V et al. Entero-cutaneous and entero-atmospheric fistulas: insights into management using negative pressure wound therapy. J Clin Med, 2024, 13 (5). doi: 10.3390/jcm13051279
[7] Luglio G, Amendola A, Pagano G et al. Combined surgical and negative pressure therapy to treat multiple enterocutaneous fistulas and abdominal abscesses: a case report. Ann Med Surg (Lond), 2020, 57: 123-126. doi: 10.1016/j.amsu.2020.06.037
[8] Stenberg K, Eriksson A, Odensten C, Darehed D. Mortality and complications after percutaneous endoscopic gastrostomy: a retrospective multicentre study. BMC Gastroenterol, 2022, 22 (1): 361. doi: 10.1186/s12876-022-02429-0
[9] Shehata M, Al Hosani I, Ahmed I et al. Factors associated with short-term complications after percutaneous endoscopic gastrostomy tube insertion: a retrospective cohort study. Cureus, 2024, 16 (3): e55741. doi: 10.7759/cureus.55741.