PREVALENCE AND ASSOCIATED FACTORS OF LATE-ONSET HYPOGONADISM AMONG MEN AGED 40 AND OLDER AT THE ANDROLOGY CLINIC OF 108 MILITARY CENTRAL HOSPITAL

Le Duc Phuc1, Nguyen Tuan Dat1, Nguyen Van Phuc1, Phan Le Nhat Long1, Pham Duc Manh1
1 108 Military Central Hospital

Main Article Content

Abstract

Objectives: To describe the prevalence of late-onset hypogonadism and analyze associated factors among men aged 40 and older at the Andrology Clinic, 108 Military Central Hospital.


Subjects and methods: A cross-sectional descriptive study was conducted on 260 men aged 40 years and above. Male hypogonadism was assessed using the ADAM questionnaire and serum testosterone concentration measurements.


Results: The highest proportion of participants belonged to the 51-60 age group (34.6%). The prevalence of symptomatic hypogonadism ADAM (+) was 54.6%, while biochemical testosterone deficiency was confirmed in 32.8% of the subjects. Statistically significant associations (p < 0.05) were identified between hypogonadism and several factors, including obesity (BMI ≥ 25 kg/m²), large waist circumference (≥ 90 cm), and the presence of underlying comorbidities.


Conclusions: The prevalence of male hypogonadism among the study subjects is considerably high and strongly associated with metabolic disorders and comorbidities. Early screening and management of metabolic risk factors play a pivotal role in improving health outcomes for aging men.

Article Details

References

[1] Ho C.C, Singam P, Hong G.E, Zainuddin Z.M. Male sexual dysfunction in Asia. Asian Journal of Andrology, 2011, 13 (4): 537-542. doi: 10.1038/aja.2010.135
[2] Nguyễn Trung Hiếu, Nguyễn Trung Kiên, Đàm Văn Cương và cộng sự. Thực trạng suy sinh dục nam tại thành phố Cần Thơ. Tạp chí Y Dược học Cần Thơ, 2025, 88: 101-108. doi: 10.58490/ctump.2025i88.3580
[3] Yi-Jun L, Xu-Bo S, Yu Na, Xue-Jun S et al. Prevalence of late-onset hypogonadism among middle-aged and elderly males in China: results from a national survey. Asian Journal of Andrology, 2021, 23 (2): 170-177. doi: 10.4103/aja.aja_59_20
[4] Đinh Xuân Dương, Nguyễn Hoài Bắc, Phạm Thị Ngọc Bích và cộng sự. Nồng độ testosterone máu và một số yếu tố liên quan ở nam giới khám sức khỏe tại Bệnh viện Đại học Y Hà Nội. Tạp chí Y học Việt Nam, 2023, 522 (1): 296-301. doi: 10.51298/vmj.v522i1.4282
[5] Bac Hoai Nguyen, Thanh Do Truong, Thang Nguyen Cao et al. Age-specific testosterone thresholds: reconsidering diagnostic criteria for hypogonadism across generations of Vietnamese men. The Aging Male, 2024, 27 (1): 2422379. doi: 10.1080/13685538.2024.2422379
[6] ScienceDirect. Hypogonadism - an overview. Pharmacology, toxicology and pharmaceutical science. Retrieved May 2, 2026. https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/hypogonadism
[7] Nguyễn Trung Hiếu, Lê Thanh Bình, Trần Huỳnh Tuấn và cộng sự. Nồng độ testosterone máu và một số yếu tố liên quan ở nam giới mắc suy sinh dục đến khám tại Bệnh viện Trường Đại học Y Dược Cần Thơ. Tạp chí Y Dược học Cần Thơ, 2023, 69: 244-250. doi: 10.58490/ctump.2023i69.2070