CHARACTERISTICS OF SLEEP DISORDERS IN BREAST CANCER PATIENTS
Main Article Content
Abstract
Objectives: To evaluate the prevalence and nature of sleep disturbances among individuals diagnosed with breast cancer receiving care at the Nuclear Medicine and Oncology Center – Bach Mai Hospital between 2025 and 2026.
Methods: A cross-sectional descriptive analysis was performed on a cohort of 180 breast cancer patients (including both inpatients and outpatients) at the Nuclear Medicine and Oncology Center – Bach Mai Hospital, from September 2025 to March 2026.
Results: The study population had a mean age of 57.5 ± 12.2 years. The study found that 55.6% of patients had been diagnosed with breast cancer for over one year; 40.6% were in stages III-IV or had distant metastasis. Insomnia was the most prevalent disorder (58.3%), followed by Restless Legs Syndrome (20.6%). Poor sleep quality (PSQI > 5) was reported in 61.1% of the patients. The odds of sleep disorders were 9.3 times higher in patients with hot flashes than in those without, and this difference was statistically significant (OR= 9,294, 95% CI: 4,647-18,587, p< 0,001).
Conclusions: Sleep disturbances are frequently observed in patients with breast cancer. Implementing systematic screening protocols and timely therapeutic interventions is vital for enhancing sleep health and the general well-being of these patients.
Article Details
Keywords
breast cancer, sleep disorders, insomnia, sleep quality, PSQI score.
References
2. Huong GN, Nguyen HL, Goldberg RJ, et al. Thirty-Year Trends (1991-2020) in Breast Cancer Incidence Rates: Hanoi, Vietnam. JCO Glob Oncol. 2025;11:e2400570. doi:10.1200/GO-24-00570
3. Gonzalez BD, Eisel SL, Qin B, et al. Prevalence, risk factors, and trajectories of sleep disturbance in a cohort of African-American breast cancer survivors. Support Care Cancer. 2021;29(5):2761-2770. doi:10.1007/s00520-020-05786-2
4. Cheng WH, Teo RH, Cheng LJ, Lau Y, Lau ST. Global prevalence of sleep disturbances among breast cancer survivors: A systematic review with meta-analysis. Sleep Health. 2023;9(5):704-716. doi:10.1016/j.sleh.2023.04.004
5. Weng YP, Hong RM, Chen VCH, Tsai CJ, Yeh DC, Fang YH. Sleep Quality and Related Factors in Patients with Breast Cancer: A Cross-Sectional Study in Taiwan. Cancer Manag Res. 2021;13:4725-4733. doi:10.2147/CMAR.S302966
6. N DG, Má MP, Cf LJ, J MF, M ND, Mc C. The need for comprehensive sleep disturbances assessment and management in breast cancer care. Sci Rep. 2025;15(1). doi:10.1038/s41598-025-05315-3
7. Martella S, Proserpio P, Guerrieri ME, et al. Insomnia in Women Surviving Breast and Gynecological Cancers—A Narrative Review to Address the Hormonal Factor. Cancers. 2025;17(24):4022. doi:10.3390/cancers17244022
8. Marell PS, Vierkant RA, Larson NL, et al. Factors associated with sleep disturbance in breast cancer survivors over time. The Oncologist. 2025;30(10):oyaf297. doi:10.1093/oncolo/oyaf297
9. Berisha A, Shutkind K, Borniger JC. Sleep Disruption and Cancer: Chicken or the Egg? Front Neurosci. 2022;16. doi:10.3389/fnins.2022.856235
10. Van Dyk K, Joffe H, Carroll JE. Sleep and endocrine therapy in breast cancer. Curr Opin Endocr Metab Res. 2021;18:165-170. doi:10.1016/j.coemr.2021.03.007