8. EVALUATION OF THE RELATIONSHIP BETWEEN SYMPTOMS AND FACTORS ASSOCIATED WITH GASTRIC COLLATERAL BLOOD STASIS SYNDROME IN PATIENTS WITH CHRONIC ATROPHIC GASTRITIS
Main Article Content
Abstract
Objective: To evaluate the clinical characteristics and associated factors of Gastric Collateral Blood Stasis syndrome in patients with chronic atrophic gastritis.
Subjects and methods: A cross-sectional descriptive study was conducted involving 400 patients diagnosed with chronic atrophic gastritis at two branches of the University Medical Center Ho Chi Minh city.
Results: The Gastric Collateral Blood Stasis syndrome pattern accounted for 19% of cases. Symptoms including abdominal distension, fixed epigastric pain, pressure-sensitive epigastric pain, dark facial complexion, dark red tongue, sublingual blood stasis, and wiry pulse showed statistically significant differences when compared to other syndromes (p < 0.05). Meanwhile, symptoms such as melena, petechiae on the tongue, and choppy pulse did not differ significantly between syndrome groups (p > 0.05).
Conclusion: Factors such as gender, history of Helicobacter pylori infection, and specific clinical symptoms demonstrated statistical significance in the diagnosis of Gastric Collateral Blood Stasis syndrome.
Article Details
Keywords
Chronic atrophic gastritis, Gastric Collateral Blood Stasis syndrome, traditional medicine.
References
[2] Nguyễn Thị Nhã Đoan. Hiệu quả của phác đồ bộ ba có Levofloxacin kết hợp với Bismuth trong tiệt trừ Helicobacter pylori. Tạp chí Khoa học Việt Nam, 2018, IX (53).
[3] Zhu Y.B, Zhu Y.P, Huang L.M et al. Clinical research progress of chronic atrophic gastritis in Traditional Chinese Medicine etiology and pathogenesis and syndrome differentiation. Zhonghua Zhong Yiyao Xue Kan, 2017, 35 (02): 322-325. doi: 10.13193/j.issn.1673-7717.2017. 02.018 (in Chinese).
[4] Wang Y.M, Sun J.H, Sun R.X et al. Treating chronic atrophic gastritis: identifying sub-population based on real-world TCM electronic medical records. Front Pharmacol, 2024, 15: 1444733. doi: 10.3389/fphar.2024.1444733.
[5] Chen L.F. Study on the relationships between the distributions of symptoms and Hp and the pathological grading of chronic superficial gastritis. Master’s Degree Thesis. Fujian University of Traditional Chinese Medicine (in Chinese), 2010.
[6] Zhang Y, Zhou A.J, Liu Y et al. Exploratory factor analysis for validating traditional Chinese syndrome patterns of chronic atrophic gastritis. Evid Based Complement Altern Med, 2016, 2016 (1): 1-12. doi: 10.1155/2016/6872890.
[7] Zhu F.S, Si J.M, Wang L.J. Study on the classification of clinical syndromes of atrophic gastritis. Shijie Huaren Xiaohua Zazhi, 2003, 11 (6): 844-846. doi: 10.11569/wcjd.v11.i6.844 (in Chinese).
[8] Tran M.N, Jun H.J, Lee S.H. Identifying the molecular mechanism of blood stasis syndrome through the symptom phenotype-genotype association approach. Medicine, 2024, 103 (49): e40717, doi: 10.1097/md.0000000000040717.
[9] Liu R, Jiang L.J, Yang Y, et al. Study on syndrome differentiation strategy of phlegm and blood stasis syndromes of coronary heart disease based on expert consultation on medical cases. Ann Palliat Med. 2021; 10 (9): 9940-9952. doi: 10.21037/apm-21-2332.
[10] Jin S.Y, Liu Y.H et al. Dark red tongue color formation caused by hyperglycemia is attributed to decreased blood flow of tongue tissue partially due to nuclear factor-kappa B pathway activation. Tradit Chin Med. 2023; 43 (6): 1118-1125. doi: 10.19852/j.cnki.jtcm.20231 018.003.